颈动脉超声对冠状动脉粥样硬化性心脏病合并缺血性脑血管疾病患者颅内动脉狭窄性病变的预测价值  

Evaluation of ischemic cerebrovascular lesions by carotid ultrasonography in patients with coronary atherosclerosis heart disease and its value for predicting cerebrovascular stenosis

作　　者：张蕾[1] 王维平[2] 李亚琼[1] 高承梅[1] 刘晶[1] 李晓辉[1] 

机构地区：[1]首都医科大学宣武医院心脏中心,北京100053 [2]河北医科大学第二医院神经内科

出　　处：《脑与神经疾病杂志》2013年第1期53-56,共4页Journal of Brain and Nervous Diseases

摘　　要：目的探讨颈动脉超声评价冠状动脉粥样硬化性心脏病(CAD)合并缺血性脑血管(ICVD)患者颅内动脉狭窄性病变的预测价值。方法对209例经血管造影证实冠状动脉狭窄(≥70%)同时合并缺血性脑血管疾病的患者采用彩色多谱勒超声(CDFI)和经颅多普勒超声(TCD)分别检查颈动脉和颅内动脉,并将患者分为脑动脉狭窄组与非狭窄组,分别比较两组患者颈动脉超声检查结果中差异有统计学意义的指标。结果颈动脉球部内-中膜(IMT)增厚、不均质回声斑块、多发斑块、颈动脉狭窄与CAD患者合并颅内动脉狭窄性病变之间具有良好的相关关系,(P<0.05)。结论颈动脉内膜增厚、不均质回声斑块,多发斑块、颈动脉狭窄与CAD合并ICVD患者颅内动脉狭窄性病变之间有明显的相关性。采用CDFI对冠状动脉狭窄的患者进行颈动脉检测,在心脑血管事件高危人群中进行筛选,对临床诊断与治疗具有重要的指导意义。Objective To evaluate the clinic value for predicting ischemic cerebrovascular atherosclerosis disease （ICVD） in patients with coronary atherosclerosis heart disease （CAD） via carotid uhrosonography. Methods CDFI and TCD were used to examine the carotid artery and intracranial artery respectively for the 209 patients whose diagnosis of coronary artery stenosis （≥ 70% ）and intracranial arterial stenosis via selective coronary angiography. The patients were divided into intracranial artery stenosis and non - intracranial artery stenosis groups. The carotid ultrasound findings variables were evaluated in the stenosis and non - stenosis groups respectively. Results There was a significant correlation between cerebrovascular stenosis disease in patients with CAD and the carotid uhrasound findings variables, including carotid maximum intima- media thickness （IMT）, heterogeneous plaque, multi - plaques and carotid stenosis （ P 〈 0.05 ）. Conclusion Cerebrovascular stenosis disease in patients with CAD has significant correlation with the carotid ultrasound findings variables, including maximum intima - media thickness （ IMT）, heterogeneous plaque, multi - plaques and carotid stenosis. Therefore, carotid ultrasonography should be applied for coronary atherosclerosis heart disease patients for the purpose of screening for high - risk groups of cardiovascular and cerebrovascular events, which could have important value for clinical practice.

关 键 词：颈动脉超声 冠状动脉狭窄 动脉粥样硬化 危险因素 

分 类 号：R743.32[医药卫生—神经病学与精神病学]