不同方法对云南少数民族儿童珠蛋白生成障碍性贫血调查结果分析  

To investigation on thalassemia among the children of the ethnic groups by the different possible screening method in YunNan

作　　者：姚莉琴[1] 邹团标[1] 全星[1] 刘锦桃[1] 冯曦云[1] 赵钟鸣[1] 王兴田[1] 

机构地区：[1]云南省妇幼保健院,昆明650051

出　　处：《检验医学与临床》2013年第2期175-177,179,共4页Laboratory Medicine and Clinic

摘　　要：目的探讨初筛检查法和完整筛查法在云南大样本珠蛋白生成障碍性贫血调查中的情况。方法采用完整筛查法筛查,即对所有调查者进行血细胞分析和电泳分析,及对先证者进行家系调查。结果完整筛查法和初筛检查法比较,无论什么年龄、性别、民族,地中海贫血检出率新平均高于元阳县,初筛检查法有漏检,新平县也高于元阳县。结论地中海贫血在云南省新平县傣族儿童中属高发,元阳县哈尼族低发。完整筛查法与初筛检查法在低发地区和民族中地中海贫血检出率差异无统计学意义。初筛检查法虽然有漏检,但可节省将近一半的人力物力,在大样本的调查中有较高的应用价值。Objective To evaluate the investigation of the different large population survey on a primary screen and complete screening in Yunnan.Methods For complete screening：All investigators were verified by blood cell automatic analysis,hemoglobin electrophoresis,and family survey was investigated.Results The detection rate of thalassaemia was higher in Xinping than in Yuanyang,There was missed in a primary screen.The missing rate was higher in Xinping than in Yuanyang.Conclusion Thalassemia is high among the children of Dai people in Xinping and low among the children of Hani people in Yuanyang of YunNan.There was no statistically significant difference of the detection rates of thalassaemia between a primary screen and complete screening in low incidence area.Although there was missed in a primary screen,But it can save nearly half of the human and material resources,There is a high value in a large population survey.

关 键 词：初筛检查法 完整筛查法 儿童 地中海贫血 少数民族 云南 

分 类 号：R725.5[医药卫生—儿科]