局部热疗联合最佳支持治疗改善消化系统肿瘤恶病质临床观察  

Clinical observation of local hypeythermia combined with best support treatments on cancer cachexia of digestive tract

作　　者：亓久德[1] 郭本成[1] 

机构地区：[1]莱芜市人民医院肿瘤科,山东莱芜271100

出　　处：《实用肿瘤杂志》2013年第1期53-56,共4页Journal of Practical Oncology

摘　　要：目的观察局部热疗联合最佳支持治疗改善消化系统肿瘤患者恶病质的有效性,为晚期肿瘤患者恶病质的姑息治疗提供有价值的临床数据。方法 58例消化系统癌性恶病质患者随机分为对照组和治疗组,对照组仅行最佳支持治疗;治疗组同时接受局部热疗治疗。进行1月前、后两组主观综合性营养评价(SGA)及实验室检查(血清白蛋白、前白蛋白、淋巴细胞总数)。结果 SGA评估结果两组比较差异有统计学意义(P<0.01)。治疗组治疗前、后血清白蛋白、前白蛋白、淋巴细胞总数比较差异均有统计学意义(P<0.01)。结论 局部热疗治疗改变了消化系统肿瘤患者恶病质的预后,有利于遏制恶病质的进展。Objective To investigate the effect of local hypeythermia combined with best support treatments （ BSC ） on cancer eachexia of digestive tract and to offer value clinical data for palliative treatments of patients with advanced malignant tumor. Methods Fifty-eight patients with cancer eaehexia of digestive tract were randomly divided into two groups, the patients in the study group （n = 30） were given local hypeythermia plus BSC, and the patients in the control group（ n = 28 ） were given BSC alone. The subjective global assessment of nutritional status（SGA） and lab examnations （ALB, pre-ALB and TLC ） after 1 month were evaluated. Results The evaluation of the SGA and ALB, pre-ALB and TLC in both groups had significant difference （ P 〈 0.01 ）. Conclusion Local hypeythermia can change the prognosis and prohibit the progressing of cancer cachexia.

关 键 词：消化系统肿瘤 恶病质 高温 诱发 综合疗法 

分 类 号：R735[医药卫生—肿瘤] R730.58[医药卫生—临床医学]