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出 处:《中国普通外科杂志》2000年第4期362-364,共3页China Journal of General Surgery
摘 要:目的 探讨胃肠道恶性黑色素瘤 (GIMM )的病因、临床特征及治疗。方法 复习相关文献并作综述性报告。结果 GIMM多为转移性的 ,原发性少见。常能找到原发皮肤病变 ,但有 4%~ 12 %无原发病灶 ,早期可引起区域淋巴结及血源性转移。临床特点 :胃肠道出血、肿块或梗阻 ,肿块有黑色素沉着。手术治疗为姑息性 ,以解除出血及梗阻症状。未经治疗的转移性GIMM预后很差。结论 胃肠道GIMM术前诊断困难 ,转移早 ,外科治疗为姑息性 ,预后差 。Objective To evaluate the etiology, clinical features and treatment of gastrointestinal malignant melanoma(GIMM). Methods Searching publications with key words as “malignant melanoma” and “gastrointestinal” from medline from 1960 to 1999 for making a review. Results Most of GIMM were metastatic, often companied by primary skin lesions, but no primary cancer could be found in 4~12 percent of the cases. Early metastasis to local lymph nodes and blood spread might exist in some patients. Clinical features include gastrointestinal bleeding, abdominal lumps, intestinal obstruction and black pigmentation were often seen on the surface of tumor. Treatment was mainly palliative to relieve bleeding or obstruction. The prognosis of secondary GIMM was rather poor. Conclusions It is difficulty to make diagnosis of GIMM before operation. This malignancy often spread early, and the operation is often palliation with poor prognosis.
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