复方儿茶胶囊联合西沙比利治疗反流性食管炎的疗效  

Treatment of reflux esophagitis by combination therapy of capsule catechu compositae and cisapride

作　　者：郑日男[1] 武寒霄 金海燕[1] 金永日[1] 朴熙绪[1] 

机构地区：[1]延边大学医学院附属医院消化内科,延吉133000 [2]牡丹江水泥集团医院,牡丹江157041

出　　处：《中国新药杂志》2000年第7期477-478,共2页Chinese Journal of New Drugs

摘　　要：目的 :观察复方儿茶胶囊联合西沙比利治疗反流性食管炎的疗效。方法 :172例反流性食管炎的患者 ,随机分为治疗及对照组各 86例 ,治疗组用西沙比利 10mg ,qid ,po ,加复方儿茶胶囊 0 .5 15 ,tid ,po ;对照组用西沙比利 10mg ,qid ,po ,每 2周复诊 1次 ,4周和 8周后再次进行胃镜检查。结果 :2组患者治疗后症状总分均明显下降 ,胃镜下反流性食管炎愈合率对照组和治疗组分别为 80 .2 %和 93% (P <0 .0 5 )。结论 :复方儿茶胶囊联合西沙比利治疗反流性食管炎 。Objective:To observe the efficacy of combination therapy of capsule catechu compositae and cisapride in treatment of reflux esophagitis.Methods:172 patients with reflux esophagitis were randomly and equally divided to receive combination therapy of 10 mg cisapride (qid) and capsule catechu compositae 0.515(tid)or cisapride 10 mg(qid). Reexamined was conducted biweekly and gastroscopic observation were conducted at 4 and 8 weeks.Results:The symptoms were significantly improved in both groups. The cure rate of esophagitis was 93% for active group and 80.2% for control group ( P <0.01).Conclusion:The combination therapy of capsule catechu compositae and cisapride is more effective in treatment of reflux esophagitis than single cisapride therapy.

关 键 词：复方儿茶胶囊 西沙比利 反流性食管炎 治疗 

分 类 号：R571.05[医药卫生—消化系统] R975[医药卫生—内科学]