浸润性导管癌钼靶X线征象:高密度与等密度肿块比较  

Comparison of high density and isodensity mass of mammography X-ray sign in patients with invasive ductal carcinoma

作　　者：徐莉[1,2] 张刚[1,2] 刘园园[1,2] 刘波[1,2] 刘岘[1,2] 岑东芝[1,2] 

机构地区：[1]广东省中医院放射科 [2]广州中医药大学博士后流动站,广州市510000

出　　处：《实用医学杂志》2013年第3期377-380,共4页The Journal of Practical Medicine

基　　金：国家自然科学基金项目(编号:30700184);广州市卫生局医药卫生科技项目(编号:20122A011032);广州中医药大学博士后基金(编号:20120621)

摘　　要：目的:比较乳腺浸润性导管癌钼靶X线中肿块高密度组与等密度组浸润性导管癌的钼靶X线征象异同。方法:回顾性分析49例浸润性导管癌的钼靶X线资料并采用t检验或两独立样本秩和检验对出现肿块征象的39例按密度分成高密度组及等密度组进行单因素分析:(1)计算Spearman相关系数,(2)比较两组包括年龄、腺体分型、侧别、象限、肿块形态、边缘、密度、肿块短径、肿块长径、钙化形态、分布、腋下淋巴结改变、乳头改变、皮肤改变、病理淋巴结转移、病理分级差异是否具有统计学意义。结果:(1)肿块密度与腺体组成成分呈中度正相关(r=0.332,P=0.039),肿块边缘呈中度负相关(r=-0.506,P=0.001),淋巴结转移呈中度负相关(r=-0.421,P=0.036)。(2)肿块高密度组较肿块等密度组腺体更少(Z=-2.048,P=0.041),边缘更不规则(Z=-2.065,P=0.039),淋巴结转移更常见(Z=-2.235,P=0.025)。结论:钼靶X线中浸润性导管癌病例出现肿块为高密度者乳腺腺体成分相对更少,肿块边缘更不规则,更多出现淋巴结病理转移,结合乳腺癌预后指数Cox预测模型,预后指数增高,患者预后差。Objective .To compare the high density and isodensity mass of mammography X-ray sign in patients with invasive ductaF carcinoma. Methods Molybdenum target X-ray data of 49 patients with invasive ductal carcinoma of breast were retrospectively analyzed, among whom 39 cases with mass sign were divided into high density group and isodensity group. The age, gland type, laterality, quadrant, mass shape, edge density, mass, short diameter, mass, length, length to diameter mass deposition morphology, distribution of calcification, axillary lymph node change, papillary changes, skin changes, pathological lymph node metastases, and pathological grading difference in both groups were recorded. Results Mass density was moderately positively correlated with glandular components （r= 0.332, P = 0.039）, and was moderately negatively correlated with mass edge （r = -0.506, P = 0.001） and lymph node metastasis （r = -0.421, P = 0.036）. Less glands （Z = -2.048, P = 0.041）, more irregular edge （Z = -2.065, P = 0.039）, and more lymph node metastasis （Z = -2.235, P = 0.025） in high density group than in isodensity group. Conclusions In patients with high density mass of mammography X-ray sign, mammary glandular components were relatively less, mass edge was more irregular, pathologic lymph node metastasis is more. As combine with breast cancer prognostic index prediction model Cox, the prognostic index is increased and prognosis is poor.

关 键 词：乳腺肿瘤 乳腺X线摄影术 病理学 

分 类 号：R737.9[医药卫生—肿瘤]