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机构地区:[1]武义县第二人民医院,浙江武义321200 [2]浙江医圣堂中医药研究所,浙江武义321200 [3]浙江中医药大学附属二院,浙江杭州310005
出 处:《中华中医药学刊》2013年第1期91-93,共3页Chinese Archives of Traditional Chinese Medicine
基 金:浙江省中医药科技计划项目(2009GA005)
摘 要:目的:观察针刺足三里、内关防治胃肠肿瘤化疗致胃肠道反应的临床疗效。方法:60例胃肠肿瘤患者随机分为两组,对照组采用格拉司琼治疗,治疗组采用足三里、内关穴针刺联合格拉司琼治疗,评价患者化疗第3 d恶心呕吐、腹胀腹痛、腹泻、便秘、口腔炎等情况。结果:治疗组与对照组比较,化疗后恶心、呕吐控制的总有效率为30%(P=0.038);治疗组化疗后腹痛控制有效率为28%(P=0.020);腹泻控制有效率为30%(P=0.010);便秘及口腔炎控制有效率分别为29%和30%(P>0.05)。结论:针刺足三里、内关联合格拉司琼防治胃肠肿瘤化疗致胃肠道反应疗效确切,安全可靠。Objective:To observe the clinical effects of needling Zusanli and Neiguan on treating gastrointestinal reactions induced by chemotherapy of gastrointestinal tumors.Methods:60 cases of gastrointestinal cancer patients were randomly divided into two groups.The control group was treated with granisetron.The treatment group was with a therapy combining granisetron and needling Zusanli and Neiguan.The first three days situations of chemotherapy patients like nausea and vomiting, abdominal pain,bloating,diarrhea,constipation,stomatitis and so on were evaluated.Results:Comparing treatment group and control group,the total effective rate of controlling nausea and vomiting was 30%(P =0.038) in the treatment group,the effective rate of controlling abdominal pain was 28%(P =0.020);the effective rate of diarrhea control was 30% (P =0.010);the effective rates of constipation and stomatitis control were 29%and 30%(P0.05 ) respectively after chemotherapy.Conclusion:The therapy combining granisetron and needling Zusanli and Neiguan is effective,safe and reliable in prevention and treatment of gastrointestinal reactions induced by chemotherapy of gastrointestinal cancer.
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