伊曲康唑治疗霉菌性食管炎疗效观察  

Efficacy observation of itraconazole in the treatment of fungal esophagitis

作　　者：朱玉周 

机构地区：[1]河南省中牟县人民医院,451450

出　　处：《临床合理用药杂志》2013年第4期11-12,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察伊曲康唑治疗霉菌性食管炎的临床疗效。方法将76例霉菌性食管炎患者随机分为试验组39例和对照组37例。试验组给予伊曲康唑治疗,对照组给予制霉菌素治疗。治疗后比较2组临床疗效及不良反应发生情况。结果试验组治愈率为97.44%高于对照组的75.68%,差异有统计学意义(P<0.05)。2组均未发现严重不良反应。结论伊曲康唑可作为霉菌性食管炎的首选治疗药物之一。Objective To observe the clinical efficacy of itraconazole in the treatment of fungal esophagitis.Methods76 cases patients with fungal esophagitis were randomly divided into test group（39 cases）and contral groups（37 cases）.Test group were treated by itraconazole,contral group were treated by nystatin,after treatment,compared the clinical efficacy and adverse reactions of two group.Results The cure rate of test group（97.44%） was higher than that of contral group（75.68%）,the difference was statistically significant（P〈0.05）.No serious adverse reactions in the course of treatment.Conclusion Itraconazole can be one of the first choice in the treatment of fungal esophagitis.

关 键 词：伊曲康唑 食管炎 霉菌性 白色念珠菌 

分 类 号：R571[医药卫生—消化系统]