声辐射力脉冲成像技术在乳腺占位性病变中的研究  

Study of acoustic radiation force impulse technology in differential diagnosis of benign and malignant breast tumors

作　　者：龚继军[1] 孙德胜[1] 钟洁愉[1] 张雁[1] 石宇[1] 鲁树坤[1] 于志强[1] 

机构地区：[1]北京大学深圳医院超声影像科,深圳市518036

出　　处：《临床超声医学杂志》2013年第1期29-31,共3页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨声辐射力脉冲成像技术(ARFI)在乳腺占位性良恶性病变鉴别诊断中的临床应用价值。方法选取72例(92个病灶)乳腺占位性病变患者和33例乳腺超声检查正常者(正常对照组),先行乳腺常规超声检查,然后使用ARFI技术检测剪切波速度(SWV),测值与术后病理结果对照,并与正常对照组对比分析。结果最终实际分析病灶数共90个,其中恶性病灶38个,SWV为(7.16±0.57)m/s,良性病灶52个,SWV为(2.71±0.74)m/s,正常对照组SWV为(1.91±0.52)m/s,两两比较差异均有统计学意义(P﹤0.05)。以SWV﹥6.2m/s作为乳腺恶性病变的诊断标准,ARFI鉴别乳腺良恶性占位病变的敏感性为91.7%,特异性为86.2%,约登指数为0.78。结论 ARFI技术可为乳腺占位性良恶性病变的早期鉴别诊断提供更多信息和依据,有重要临床应用价值。Objective To investigate the clinical value of Acoustic Radiation Force Impulse （ARFI）technology in differential diagnosis of benign and malignant breast tumors. Methods Seventy-two patients with 92 breast space-occupying- lesions and 33 patients with breast ultrasonography of normal persons （normal control group ） were first examined by breast routine ultrasound examination,and then the ARFI technology to determine the shear wave velocity （SWV）,measured values were compared with postoperative pathological results, and normal control group comparison.Results The final analysis number of the lesions were 90, among the 38 malignant lesions of which, SWV was （7.16±0.57） m/s, 52 benign lesions, SWV was （2.71±0.74） m/s, and the SWV of normal control group was （ 1.91±0.52 ） m/s, there was significant difference between the two groups （P 〈 0.05 ）. using greater than 6.2 m/s as a breast malignant space-occupying diagnostic criteria,the sensitivity and the specificity of ARFI indetifying breast benign and malignancy space-occupying lesions were 91.7% and 86.2% respectively, the Youden＇s index was 0.78.Conclusion ARFI can provide more information and basis for early differential diagnosis of breast benign and malignant lesions, which has an important clinical application value.

关 键 词：声辐射力脉冲技术 弹性成像 剪切波 乳腺肿瘤 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]