手机微波辐射对体外培养大鼠晶状体Bax表达的影响  

Influence induced by mobile microwave on the expression of Bax in the lens epithelial cells of rat in vitro

作　　者：史凯[1] 张文芳[1] 刘瑜[1] 李春丽[1] 

机构地区：[1]兰州大学第二医院眼科,中国甘肃省兰州市730030

出　　处：《国际眼科杂志》2013年第2期265-266,共2页International Eye Science

摘　　要：目的:探讨手机辐射对体外培养大鼠晶状体上皮细胞中Bax表达的影响。方法:采用ELISA和免疫组织化学法检测手机辐射后在MEM培养液培养28d晶状体中Bax的表达水平,裂隙灯下观察晶状体的混浊程度。结果:手机辐射组Bax的表达量均显著高于对照组(P<0.05),Bax的表达量随着手机辐射时间的增加而增加,且手机辐射组的晶状体混浊程度较对照组明显增加。结论:手机微波辐射可增加体外大鼠晶状体中Bax的表达,导致晶状体上皮细胞凋亡和白内障的发生。AIM： To study the effect of mobile microwave on the expression of Bax in the lens epithelial cells of rat in vitro. METHODS： Bax expression was detected by ELISA and immunohistochemistry after the lenses of rats were cultivated in MEM culture medium. RESULTS： The expression of Bax in the mobile microwave groups was significantly higher than the control group （ P〈 0.05） and the expression of Bax accumulated while it was exposed in the mobile microwave. CONCLUSION： Mobile microwave can induce the expression of Bax in the lens epithelial cells of rat and cause cataract.

关 键 词：手机辐射 BAX 晶状体 免疫组织化学 

分 类 号：R776[医药卫生—眼科]