邻苯二甲酸二甲酯印迹聚合物的制备及其在固相萃取中的应用  

Preparation of dimethyl phthalate imprinted polymers and its application in solid phase extraction

作　　者：杨顺香[1] 王腾[1] 曾莉 成会玲[2] 彭君[1] 朱秀芳[1] 曹秋娥[1] 丁中涛[1] 

机构地区：[1]云南大学化学科学与工程学院教育部自然资源药物化学重点实验室,云南昆明650091 [2]昆明理工大学理学院,云南昆明650093

出　　处：《云南大学学报（自然科学版）》2013年第1期76-82,共7页Journal of Yunnan University(Natural Sciences Edition)

基　　金：云南大学第四届研究生科研基金项目(ynuy201119)

摘　　要：制备了对增塑剂邻苯二甲酸二甲酯(DMP)具有特异选择性的印迹聚合物(MIP)并成功用于水样中DMP的固相萃取.改变功能单体和聚合方法制备了4种DMP印迹聚合物,并用平衡吸附方法研究了各聚合物对DMP及结构类似物的吸附选择性.进一步将优化聚合物MIP3用作固相萃取(SPE)柱填料,结合气相色谱-质谱联用仪(GC-MS)研究其对某环境水样中DMP的萃取能力.结果表明,MIP3可选择性富集水样中的DMP和净化干扰物质.萃取后DMP的质量浓度由8.2μg/L浓缩至80.06μg/L,富集倍数达到了9.76.回收率为99.16%～103.97%,而传统的液液萃取回收率仅为87.73%～96.14%,方法的灵敏度大大提高,检出限由0.04μg/L降低至0.007μg/L.An imprinted polymer selective to plasticizer dimethyl phthalate（DMP） was developed and applied to solid phase extraction media to extract DMP in an environmental water sample successfully.Four imprinted polymers were prepared with varied functional monomers and polymerization methods.Their binding activities to DMP and its analogue dibutyl phthalate（DBP）were estimated by equilibrium adsorption experiments.The optimized polymer MIP3 was further used as a solid phase extraction material to enrich DMP in an environmental water sample.The obtained data from gas chromatography-mass spectrometry（GC-MS） analysis showed an excellent selectivity of MIP3 to DMP in the real sample.DMP was enriched from 8.2 μg/L to 80.06 μg/L with an enrichment factor as 9.76.The system gave better average recoveries between 99.16%~103.97% and a lower limit of detection（LOD,S/N=5） as 0.007 μg/L for DMP compared to a traditional liquid-liquid extraction method（0.04 μg/L）.

关 键 词：分子印迹 固相萃取 邻苯二甲酸二甲酯 气相色谱-质谱联用 

分 类 号：TQ414.1[化学工程]