原发性中枢神经系统血管炎的MRI诊断  

MRI diagnosis of primary angiitis within central neural system

作　　者：牛磊[1] 朱蒙蒙[1] 王明皓[1] 崔文[1] 刘圆圆[1] 

机构地区：[1]南京鼓楼医院集团宿迁市人民医院,江苏宿迁223800

出　　处：《实用放射学杂志》2013年第1期8-10,14,共4页Journal of Practical Radiology

摘　　要：目的 分析原发性中枢神经系统血管炎（PACNS）的MRI表现与特征，探讨MRI对该病的诊断价值。方法回顾性分析19例PACNS的临床资料，所有病例均行MRI平扫及增强扫描。结果19例患者头颅MRI发现异常，病变主要呈T1稍低、T2稍高信号，FLAIR呈较高信号，DWI病变呈等及稍高信号，ADC图呈高信号（19例）。增强扫描19例呈斑片状、条索状、脑回状强化。7例为单侧病变，12例为双侧病变，多数病灶边界模糊，累及灰质和白质，部分有水肿。结论 PACNS具有特征性的MRI表现，DWI、ADC及MRI增强扫描对于早期明确诊断和指导治疗具有非常重要的意义。Objective To explore the features of MRIin patients with primary angiitis within central neural system（PACNS） and evaluate the diagnostic value of MRI for this disease. Methods The clinical data of 19 patients with PACNS were retrospectively ana lyzed. All cases were scanned by unenhanced and enhanced MRI. Results All cases showed lesions on cerebral MRI, which presen ted as slightly hypointensity on T1 WI, slightly hyperintensity on Te WI, rernarkahly hyperintensity on FLAIR, iso or slightly hyper- intensity on DWI and remarkably hyperintensity on ADC（ 19 cases）. After contrast injection, the lesions showed patchy, cord-like or gyrus-like enhancement. Seven cases showed unilateral lesions, while the other 12 cases had bilateral lesions. Blurry margin was found in most lesions. The lesions involved both gray and white matter. Edema was seen around some lesions. Conclusion PACNS has certain features on MRI, and DWI, ADC map and enhanced MRI were important for the diagnosis and the direction of therapy of PACNS at early stage.

关 键 词：中枢神经系统 血管炎 磁共振成像 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]