血清铜、锌、硒与恶性淋巴瘤关系的研究  

Study on Serum Copper, Zinc and Selenium in Patients with Malignant Lymphoma

作　　者：郝吉庆[1] 孙国平[1] 洪素珍[1] 

机构地区：[1]安徽医科大学第一附属医院,合肥230022

出　　处：《广东微量元素科学》2000年第3期29-32,共4页Trace Elements Science

摘　　要：测定了 68例恶性淋巴瘤患者血清铜、锌、硒及铜 /锌比值水平 ,采用t检验和非条件Logistic回归因素分析方法对测定结果进行分析。结果表明 ,恶性淋巴瘤患者血清铜、铜 /锌比值升高 ,而血清锌及硒水平降低。血清铜和铜 /锌比值升高与肿瘤的负荷状态及病期明显有关。提示血清铜和铜 /锌比值的测定对监测恶性淋巴瘤患者的病情变化有一定价值。非条件Logistic多因素分析表明 ,血清锌、硒可能是恶性淋巴瘤发病的保护因素 ;而铜 /锌比值可能是危险指标。The concentrations of serum copper, zinc, selenium and copper/zinc ratio in 68 patients with malignant lymphoma were determined and analysed by t test and non-condition logistic regression factors. The results showed that serum copper concentration and coper/zinc ratio in patients increased while serum zinc and selenium concentration decreased. There is a significant correlation between the incremental concentration of serum copper and copper/zinc ratio and the load and phase of the disease. The result indicated that serum copper concentration and copper/zinc ratio would be of great value in supervising the change of patients with malignant lymphoma. The analytical result of non-conditon logistic multiple factors indicated that serum zinc and selenium concentration may be the protective factors of malignant lymphoma,while copper/zinc ratio may be on the contrary.

关 键 词：恶性淋巴瘤 铜 锌 硒 血清 

分 类 号：R730.263[医药卫生—肿瘤]