经颅多普勒超声检测脑动脉狭窄的临床研究  

Clinical study on cerebral artery stenosis detected by transcranial Doppler ultrasound

作　　者：周京晶[1] 史佳云[1] 任润涛[1] 张健[1] 

机构地区：[1]首都医科大学附属北京友谊医院医疗保健中心,北京100050

出　　处：《临床和实验医学杂志》2013年第4期266-267,270,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的调查体检人群中脑动脉狭窄的发生率及分布规律,为其他影像检查及颈内动脉血管内膜剥脱手术(CEA)和支架置入血管成形术(CAS)提供依据。方法以参加常规体检的3 953人为研究对象,采用经颅多普勒超声(TCD)检测颅内外动脉情况。结果 3 953位体检者中,男性2 687人(67.97%),女性1 266人(32.03%)。检出动脉狭窄111人次(2.81%),134例次(3.39%)。其中男性77人(69.37%),女性34人(30.63%),男性及女性发生动脉狭窄的比率与男性及女性体检人数占总人数的比率相当(P>0.05)。发生狭窄者平均年龄(61.93±13.43)岁,男性发生狭窄平均年龄为63.21岁,女性发生狭窄平均年龄60.53岁,男性与女性发生动脉狭窄年龄无显著差异(P>0.05)。134例次动脉狭窄患者中颅内血管狭窄85例(占狭窄血管的63.43%),颅外血管49例(占狭窄血管的36.57%)。55岁以下组1 315人,脑动脉狭窄26人,占1.98%;>55岁组2 638人,发生脑动脉狭窄49人,占1.86%,≤55岁年龄组与>55岁年龄组发生脑动脉狭窄的比率差异无显著性(P>0.05)。结论 TCD可检出无症状脑动脉狭窄,因无创、简便、准确、快速、经济、可实时评价等特点适宜于普查,可作为中老年人群体检的常规项目。Objective To survey the incidence and distribution of stenosis in cerebral artery in order to provide the basis for other imaging methods and carotid artery endarterectomy（CEA） and stent angioplasty（CAS）.Methods In a routine check-up of 3953 persons as research subjects,by using transcranial Doppler ultrasound（transcranial Doppler,TCD） detection of intracranial and extracranial arterial conditions.Results Among 3953 persons in detection of arterial stenosis,2687 were men accounted for 67.97%（2687）,and 1266 were women accounted for 32.03%（1266）.Artery stenosis was found in 111 persons（2.81%）,among them males were 77（69.37%） and females 34（30.63%）.The ratio for males and females participated in this examination and ratio of artery stenosis in males and females were equavalent（P0.05）.The average age for artery stenosis was 61.93±13.43 years old,the occurrence of stenosis in men was at mean age of 63.21 years old,and in women with an average age of 60.53 years old.No significant difference in distribution of age in men and women occurring artery stenosis（P0.05）.In 134 cases of arterial stenosis,intracranial vascular stenosiswas seen in 85 cases（representing narrow vessels of 63.43%）,and 49 cases with extracranial vessels（accounted for 36.57%）.A group of 1315 persons below 55 years of age,cerebral artery stenosis was seen in 26 persons,accounted for 1.98%;in group of 2638 persons aged over 55,cerebral artery stenosis was seen in 49 persons,accounted for 1.86%;in ≤ 55years old age group and 55-year-old age group,the difference in ratio of cerebral artery stenosis was not statistically significant（P0.05）.Conclusion CD ultrasonography is a noninvasive,convenient,accurate,fast,economic and real-time evaluation of characteristics,it is suitable for application in census,and it can be used as routine physical examination project for middle and elder aged persons.

关 键 词：经颅多普勒超声 脑动脉狭窄 体检 

分 类 号：R743.3[医药卫生—神经病学与精神病学]