功能性消化不良患者抑郁焦虑状态分析  

The state of anxiety and depression in the patients with functional dyspepsia

作　　者：樊力红[1] 林真真[2] 梁普莹[2] 

机构地区：[1]广州医学院第一附属医院消化内科,510120 [2]广州医学院第一附属医院精神心理科,510120

出　　处：《中国实用医刊》2013年第5期42-45,共4页Chinese Journal of Practical Medicine

基　　金：基金项目：广东省医学科研课题项目（A2011249）

摘　　要：目的分析功能性消化不良患者（FD）的症状与抑郁焦虑状况的相关关系。方法按罗马Ⅲ标准将120例功能性消化不良患者分为餐后不适综合征（PDS）和上腹疼痛综合征（EPS）两组，设立对照组，入组者按标准完成焦虑自评量表（SAS）和抑郁自评量表（SDS）。通过SPSS16．0统计软件分析FD患者的焦虑抑郁状态，以及FD分型、重叠肠易激综合征（IBS）与抑郁焦虑状况的相互关系。结果①FD组合并焦虑状态率为63．3％，抑郁率为70％；对照组合并焦虑状态率为19．2％，抑郁率为7．5％，FD组高于对照组，差异有统计学意义（P〈0．05）。②PDS组合并焦虑、抑郁状态率分别是69．8％、73．6％，EPS合并焦虑、抑郁状态率为58．2％、67．2％，两组比较差异无统计学意义（P〉0．05）。③将所有患者分为无IBS组（81例）与重叠IBS组（39例），无IBS组无焦虑者占51．9％，合并焦虑率者占48．1％；无抑郁率为37．0％，合并抑郁率为63．0％。重叠IBS组无焦虑者占5．1％，合并焦虑者占94．9％；无抑郁率为15．4％，合并抑郁率为84．6％。重叠IBS组合并焦虑率、抑郁率均高于无IBS组，两组比较差异有统计学意义（P〈0．05）。④PDS组（53例）重叠便秘型IBS占33．9％，腹泻型IBS占1．9％，无一例混合型和未定型患者，无IBS率为64．2％；EPS组（67例）重叠便秘型IBS占7．5％，腹泻型IBS占20．9％，混合型占1．5％，无一例未定型患者，无IBS率为70．1％，PDS组与EPS组合并IBS亚型的构成比不同。结论FD患者合并焦虑抑郁状态率较高，PDS组和EPS组的焦虑抑郁率比较差异无统计学意义（P〉0．05）；FD重叠IBS者合并焦虑抑郁率高于单纯FD患者；PDS组中重叠便秘型IBS的比例高于EPS组．EPS组重叠腹泻型IBS的比例高于PDS组。Objective To analyze the realationship of anxiety and depression states in the pa tients with functional dyspepsia. Methods The patients with functional dyspepsia（FD） were divided in to two groups which included postprandial distress syndrome （PDS） and epigastria pain syndrome （EPS）. Set control group. All the candidates had finished the self rating scale in anxiety and depression. The relationship between the FD patients＇ state of depression and anxiety and Roma Ⅲ subtypes, overlapping irritable bowel syndrome（IBS） was analyzed by SPSS 16.0. Results （1）The ratios of anxiety and depression state in the FD patients （63.3% , 70% ） were higher than that of control group （ 19.2% , 7.5% ）. （2）The ratios of anxiety and depression state in the PDS were 69. 8% and 73.6% , and those in the EPS were 58.2% and 67.2%. There was no significantly different between the two groups. （3）ln the FD group no overlapping IBS, the ratios of no accompanied by anxiety and depression were 51.9% and 37.0% , and the ratios of accompanied by anxiety and depression were 48.1% and 63.0%. In the group of FD overlapping IBS, the ratios of no accompanied by anxiety and depression were 5.1% and 15.4%, and the ratios of accompanied by anxiety and depression were 94.9% and 84.6%. There were significant differences in the ratios of anxiety and depression state between FD overlapping IBS and its counterpart no overlapping IBS. （4）The ratios of IBS-constipation, IBS-diarrhea, iBS-mix, non IBS in the PDS were 33.9%, 1.9%, 0, 64.2% and those in the EPSwere7.5%, 20.9%, 1.5%, 70.1%. It was significantly different between the PDS and the EPS. Conclusions The ratios of anxiety and depression state in the FD patients were higher than that of control group. The patients with FD overlapping IBS were accompanied by anxiety and depression state more commonly than the counterpart not overlapping IBS. The ratio of IBS-constipation in the PDS was higher than that in the EPS and the ratio of IBS-diarrhea in theEPS was highe

关 键 词：功能性消化不良 焦虑 抑郁 肠易激综合征 

分 类 号：R57[医药卫生—消化系统]