Treatment of radiation-induced hemorrhagic gastritis with prednisolone:A case report  

作　　者：Lan Zhang Xiao-Ying Xie Yan Wang Yan-Hong Wang Yi Chen Zheng-Gang Ren 

机构地区：[1]Liver Cancer Institute,Zhongshan Hospital,Fudan University [2]Key Laboratory of Carcinogenesis and Cancer Invasion,Ministry of Education,Fudan University

出　　处：《World Journal of Gastroenterology》2012年第48期7402-7404,共3页世界胃肠病学杂志（英文版）

摘　　要：Radiation-induced gastritis is an infrequent cause of gastrointestinal bleeding.It is a serious complication arising from radiation therapy,and the standard treatment method has not been established.The initial injury is characteristically acute inflammation of gastric mucosa.We presented a 46-year-old male patient with hemorrhagic gastritis induced by external radiotherapy for metastatic retroperitoneal lymph node of hepatocellular carcinoma.The endoscopic examination showed diffuse edematous hyperemicmucosa with telangiectasias in the whole muscosa of the stomach and duodenal bulb.Multiple hemorrhagic patches with active oozing were found over the antrum.Anti-secretary therapy was initiated for hemostasis,but melena still occurred off and on.Finally,he was successfully treated by prednisolone therapy.We therefore strongly argue in favor of perdnisolone therapy to effectively treat patients with radiation-induced hemorrhagic gastritis.Radiation-induced gastritis is an infrequent cause of gastrointestinal bleeding.It is a serious complication arising from radiation therapy,and the standard treatment method has not been established.The initial injury is characteristically acute inflammation of gastric mucosa.We presented a 46-year-old male patient with hemorrhagic gastritis induced by external radiotherapy for metastatic retroperitoneal lymph node of hepatocellular carcinoma.The endoscopic examination showed diffuse edematous hyperemicmucosa with telangiectasias in the whole muscosa of the stomach and duodenal bulb.Multiple hemorrhagic patches with active oozing were found over the antrum.Anti-secretary therapy was initiated for hemostasis,but melena still occurred off and on.Finally,he was successfully treated by prednisolone therapy.We therefore strongly argue in favor of perdnisolone therapy to effectively treat patients with radiation-induced hemorrhagic gastritis.

关 键 词：Hemorrhagic gastritis Radiation Prednisolone Hepatocellular carcinoma Gastrointestinal bleeding 

分 类 号：R573.3[医药卫生—消化系统]