非酒精性Wernicke脑病的MRI表现  

MR findings of nonalcoholic Wernicke encephalopathy

作　　者：刘璐[1] 郝金钢[1] 闫东[1] 

机构地区：[1]昆明医科大学第二附属医院放射科,昆明650101

出　　处：《影像诊断与介入放射学》2012年第6期403-405,共3页Diagnostic Imaging & Interventional Radiology

摘　　要：目的探讨非酒精性Wernicke脑病的MRI表现。方法回顾性分析经临床证实的7例非酒精性Wernicke脑病的MRI影像资料。结果病变累及双侧丘脑6例,中脑导水管周围5例,第三脑室周围4例,第四脑室周围1例,桥脑2例,小脑蚓部1例;具体表现为T_1WI上呈低或等信号,T_2WI上呈稍高信号,FLAIR上呈高信号,DWI上呈高信号。2例行增强扫描,未见异常强化。结论非酒精性Wernicke脑病的MRI表现具有一定特征性,结合病史可以早期明确诊断。Objective To determine the MRI features of nonalcoholic Wernicke encephalopathy. Methods MRI of 7 patients with nonalcoholic Wernicke encephalopathy was analyzed retrospectively. Results MRI appearance of nonalcoholic Wernicke encephalopathy included slightly low or intermediate T1 signal intensities, symmetrically high T2 signal intensities, and hyperintensities on FLAIR- and diffusion-weighted imaging in the bilateral thalami （6）, peri- aqueductal gray matter （5）, pons （2）, cerebellar vermis （1）, around the third ventricle （4） and fourth ventricle （1）. In the two patients with contrast-enhanced imaging, there was no abnormal enhancement. Conclusion MRI features are specific and can suggest the diagnosis of nonalcoholic Wernicke encephalopathy with appropriate clinical history.

关 键 词：韦尼克脑病 磁共振成像 维生素B1 

分 类 号：R742[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]