颞叶和额叶癫痫认知功能特点的研究  

Study of cognitive function features in temporal lobe and frontal lobe epilepsy

作　　者：杨二娟[1] 毓青[1] 白学军[2] 陈英[1] 杨卫东[3] 陈旨娟[3] 郭华爱[1] 

机构地区：[1]天津医科大学总医院神经内科,天津300052 [2]天津师范大学心理与行为研究院,天津300074 [3]天津医科大学总医院神经外科,天津300052

出　　处：《天津医科大学学报》2013年第1期70-72,共3页Journal of Tianjin Medical University

摘　　要：目的:研究颞叶和额叶癫痫患者的认知功能特点。方法:对20例颞叶癫痫、16例额叶癫痫患者及15例健康对照组进行注意力、执行功能和记忆力等方面的神经心理评估。所用的认知评定工具包括工作记忆测试、听觉词语学习测验、Rey-Osterrieth复杂图片测验等。结果:颞叶和额叶癫痫组在注意力、执行功能和记忆力等方面测试成绩均落后于对照组,且差异有统计学意义(P<0.05);额叶癫痫组注意力、工作记忆、抑制控制能力、语词记忆、图形记忆减退较颞叶癫痫组明显,颞叶癫痫组语词记忆遗忘程度较额叶癫痫组大,且差异有统计学意义(P<0.05)。结论:颞叶和额叶癫痫患者均存在广泛的认知功能损害,额叶癫痫患者多项认知功能损害较颞叶癫痫明显,颞叶癫痫患者比额叶癫痫更易出现语词材料的遗忘。Objective： To investigate the features of cognitive function in temporal lobe epilepsy （TLE） and frontal lobe epilepsy（FI,E）. Methods： 20 subjeets with TLE, 16 with FLE, and 15 control subjects underwent neuropsypsychological assessment of attension, executive functions, and memory components. A series of neutopsychologic tests comprised Working memory test, Auditory verhal memory test （AVMT）, Rey-Osterrieth eomplax figure test （CFT-R-O）, etc. Results： Attention, executive functions,memory were impaired in both TI,E and FLE （P 〈0.05）. Attention,working memory,control / inhibition,verbal and nonverbal memory deficit were greater in FLE than in TLE（P 〈0.05）. Verbal memory was impaired much in TLE than in FLE. Conclusion： Cognitions in both TLE and FI,E have widely deficts, especially in FLE. Verbal memory is forgotten easily in TLE than in FLE.

关 键 词：癫痫 颞叶 额叶 认知功能 神经心理学 

分 类 号：R742.1[医药卫生—神经病学与精神病学]