黄山杜鹃总黄酮的体外抗氧化活性研究  

Study on in vitro antioxidant activity of total flavonoids from Rhododendron anhwiense

作　　者：邢懿[1] 梁波[1] 汪璐[1] 张磊[1] 毕淑峰[1] 

机构地区：[1]黄山学院生命与环境学院,安徽黄山245041

出　　处：《华西药学杂志》2013年第1期53-55,共3页West China Journal of Pharmaceutical Sciences

基　　金：黄山学院博士启动基金项目(项目编号:2012xkjq002);黄山学院大学生创新基金项目(项目编号:2012xdkj016)

摘　　要：目的研究黄山杜鹃总黄酮的抗氧化活性。方法采用体外实验研究黄山杜鹃总黄酮的还原力、金属螯合性及对1,1-二苯基苦基苯肼自由基(DPPH.)、超氧阴离子自由基(O2-.)、亚硝酸钠的清除能力。结果黄山杜鹃总黄酮提取液的浓度为505 mg.L-1,总黄酮提取液有很好的还原力和金属离子的螯合能力;总黄酮对DPPH.、O2-.和亚硝酸钠有清除作用,且存在量效关系。结论黄山杜鹃总黄酮在体外具有抗氧化活性。OBJECTIVE To study antioxidant activity of total flavonoids from Rhododendron anhwiense Wils..METHODS The reducing power,metal chelating ability,scavenging capacity against DPPH·,superoxide anion free radical and sodium nitrite in vitro were investigated.RESULTS The concentration of the total flavonoids of Rhododendron anhwiense was 505 mg·L-1.The total flavonoids exhibited strong reducing power and metal chelating ability.At the same time,the total flavonoids had scavenging capacity against DPPH·,superoxide anion free radical,and sodium nitrite in a concentration-dependent fashion.CONCLUTION The total flavonoids from Rhododendron anhwiense Wils.possess an antioxidant activity in vitro.

关 键 词：黄山杜鹃 总黄酮 抗氧化活性 清除能力 

分 类 号：R96[医药卫生—药理学]