无线动力胶囊技术的应用  

Rationale for clinical use of wireless motility capsule

作　　者：李苗苗[1] 叶必星[1] 林琳[1] 

机构地区：[1]南京医科大学第一附属医院消化内科,江苏省南京市210029

出　　处：《世界华人消化杂志》2013年第2期166-170,共5页World Chinese Journal of Digestology

摘　　要：无线动力胶囊技术(wireless motility capsule,WMC)是国外近年来兴起的一项胃肠动力检测技术,通过胶囊在消化道内运行并实时记录pH、温度、压力信息间接计算出胃排空时间(gastric emptying time,GET)、小肠转运时间(small bowel transit time,SBTT)、结肠转运时间(colonic transit time,CTT)和全胃肠道转运时间(whole gut transit time,WGTT).特别适用于可疑多区域胃肠动力异常的患者.美国食品和药物管理局(food and drug administration,FDA)已批准WMC用于胃轻瘫患者胃排空时间的检测、胃窦十二指肠压力描述及慢性便秘患者结肠转运时间的检测.现对WMC技术的原理和应用作一综述.The wireless motility capsule （WMC） is a recently developed technique for evaluating gastrointestinal motility. As the capsule moves through the gastrointestinal tract, it allows for real-time measurement of the pH, temperature and pressure of its surrounding environment to indirectly calculate gastric emptying time （GET）, small bowel transit time （SBTT）, colonic transit time （CTT） and whole gut transit time （WGTT）. The WMC is especially suitable for patients suspected of dysmotility in more than one region in the gastrointestinal tract. The US FDA has approved the WMC for the evaluation of gastric emptying time in patients with suspected gastroparesis and colonic transit time in patients with suspected chronic constipation, and for the characterization of antral and duodenal pressure profiles. In addition, the WMC has been tested as an alternative to scintigraphy and radiopaque marker technology in several clinical trails. This review summarizes the rationale for clinical use of the WMC.

关 键 词：无线动力胶囊 胃肠动力 胃肠压力 胃轻瘫 便秘 

分 类 号：R57[医药卫生—消化系统]