运用E-Tracking技术检测酒精性肝病患者戒酒治疗前后颈动脉弹性变化的研究  

Study of carotid artery elasticity of the patients with alcoholic liver disease before and after abstinence from alcohol by ultrasonic E-Tracking imaging technology

作　　者：刘景云[1] 吴文治[2] 戴珂珂[1] 胡元平[1] 周漫[1] 朱雪莲[1] 

机构地区：[1]温州医学院附属第一医院超声影像科,浙江325000 [2]温州医学院附属第一医院 消化内科,浙江325000

出　　处：《影像诊断与介入放射学》2012年第5期332-334,共3页Diagnostic Imaging & Interventional Radiology

基　　金：温州市科技局资助项目<血管回声跟踪技术检测酒精性肝病患者颈动脉弹性与血管内皮舒张功能相关性的研究>;项目编号:Y20090069

摘　　要：目的运用E-Tracking技术检测酒精性肝病(ALD)患者戒酒治疗前后颈动脉弹性的变化。方法 ALD患者137例,戒酒组31例,戒酒失败组106例,常规颈动脉超声获取治疗前后IMT、D、RI、PI、S/D几项指标,运用E-Tracking技术获取治疗前后Ep、β、AC、AI、PWVβ指标。比较两组治疗前后常规超声指标及E-Tracking指标;比较戒酒组中,不同程度肝损伤的各类在戒酒治疗前后E-Tracking指标。结果戒酒组与戒酒失败组治疗前后常规超声指标无明显差异,戒酒组治疗后Ep、β、PWVβ治疗前减低,AC增高,差异有统计学意义(P<0.05或P<0.01),戒酒失败组各项参数差异无统计学意义;戒酒组中,酒精性脂肪肝(AFL)及酒精性肝炎(AH)患者E-Tracking指标较酒精性肝硬化(AC)患者变化显著。结论 ALD患者戒酒治疗后颈动脉硬度、弹性减低、顺应性增高、扩张性降低,尤以酒精性脂肪肝及酒精性肝炎患者更为明显,E-Tracking技术能准确定量评价颈动脉弹性,为临床评价ALD治疗效果提供了一种新的方法。Objective To study the carotid artery elasticity of the patients with alcoholic liver disease（ALD） before and after abstinence from alcohol by uhrasonic E-Tracking imaging technology. Methods β patients abstinence from alcohol and 106 patients who failed to abstinence from alcohol were included. Common carotid artery （CCA） was checked by routine ultrasonic imaging and IMT, D, RI, PI and S/D were measured. By E-Tracking imaging technology, parameters include stiffness pressure-strain elastic modulus （Ep）, stiffness parameters （β）, arterial compliance （AC）, augmentation index （AI）, and pulse wave velocity（PWVI3） were measured. Results There were no significant differences in IMT, D, RI, PI, S/D and AI between the two groups （P〉0.05）. In abstinence from alcohol group, Ep, β, and PWVβwere significantly lower （P〈O.01 or 0.05） and AC was significantly higher （P〈0.01） after the therapy. There were no significant differences of E-Tracking parameters in patients who failed to abstinence from alcohol. In abstinence from alcohol group, the differences of E-Tracking parameters were more significant in patients with AFL and AH than those with AC. Conclusion The loss of elasticity, stiffness, diastolic function and the reinforce of compliance occurred in the patients with ALD abstinence from alcohol, especially in the patients with AFL and AH . E-Tracking technology is an accurate quantitative method for evaluating the curative effect on ALD patients.

关 键 词：回声跟踪技术 酒精性肝病 戒酒 颈动脉 动脉弹性 

分 类 号：R575[医药卫生—消化系统]