疏血通注射液治疗急性脑梗死的临床观察  

Clinical Observation of Shuxuetong Injection in the Treatment of Acute Cerebral Infarction

作　　者：王昕[1] 谢代鑫[1] 赵立波[1] 刘华[1] 孙后超[1] 

机构地区：[1]重庆市第三人民医院神经科,重庆400014

出　　处：《中国药房》2013年第8期709-711,共3页China Pharmacy

摘　　要：目的:观察疏血通注射液治疗急性脑梗死的效果。方法:将71例急性脑梗死患者分为治疗组(36例)和对照组(35例)。对照组给予常规对症治疗,治疗组在对照组的基础上加用疏血通注射液6ml,缓慢静脉滴注。两组均治疗3周。治疗前、后检测患者的血液流变学指标[全血高切黏度、全血低切黏度、血浆比黏度、纤维蛋白原、血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板比积(PCT)],观察两组的疗效及不良反应。结果:两组治疗后全血高切黏度、全血低切黏度、血浆比黏度、纤维蛋白原、MPV、PDW显著下降,PLT显著升高,与治疗前比较差异均有统计学意义(P<0.05);且治疗组各项指标改善情况显著优于对照组,差异也有统计学意义(P<0.05)。治疗组总有效率为91.67%,与对照组(74.29%)比较有显著性差异(P<0.05)。试验中两组均未见不良反应发生。结论:疏血通注射液治疗急性脑梗死安全、有效。OBJECTIVE： To observe the clinical efficacy of Shuxuetong injection in the treatment of acute cerebral infarction. METHODS： 71 cases of cerebral infarction were divided into treatment group （36 cases） and control group （35 cases）. Control group received routine symptomatic treatment. Treatment group was additionally given intravenous drip of Shuxuetong injection 6 ml slowly. Treatment course of 2 groups lasted for 3 weeks. The hemorheological indexes were detected [whole blood viscosity, blood viscosity, plasma viscosity, fibrinogen, platelet count （PLT）, mean platelet volume （MPV）, platelet distribution width （PDW）, platelet hematocrit （PCT）]. Therapeutic efficacy and adverse drug reaction were evaluated according to clinical efficacy evaluation criteria. RESULTS： The whole blood viscosity, blood viscosity, plasma viscosity, fibrinogen, MPV and PDW de- creased significantly while PLT increased in 2 groups after treatment, there were significant differences （P〈0.05）. There was statis- tical significance in the improvement of index between 2 groups （P〈0.05）. The total effective rate of treatment group was 91.67%, there were significant differences, compared with control group （74.29%）. No adverse drug reaction occurred in both groups. CONCLUSION： Shuxuetong injection is safe and effective in the treatment of acute cerebral infarction.

关 键 词：疏血通注射液 急性脑梗死 血液流变学 疗效 

分 类 号：R743[医药卫生—神经病学与精神病学]