牙源干细胞在再生医学中的应用  

Application of dental stem cells in tissue regeneration

作　　者：宋芳[1] 邹慧儒[1] 

机构地区：[1]天津市口腔医院牙体牙髓病科,天津300041

出　　处：《国际口腔医学杂志》2013年第2期224-228,共5页International Journal of Stomatology

基　　金：天津市卫生局科技基金资助项目(2012KY19)

摘　　要：干细胞可修复受损组织并保存组织功能。牙源干细胞是间充质干细胞,更适用于组织工程,其多向分化潜能不仅可分化为成牙细胞,而且还可分化为神经细胞、成骨细胞、软骨细胞和脂肪细胞。牙源干细胞主要有牙髓干细胞、牙周膜干细胞、根尖乳头干细胞和脱落乳牙牙髓干细胞等。在再生医学中,利用牙源干细胞再生牙组织,将会是一种新的医疗模式。Stem cells research has grown exponentially owing to their ability to rescue and repair injured tissue and partially restore organ function. The dental stem cells are considered rich sources of mesenchymal stem cells that are suitable for tissue engineering applications. These stem cells have the potential to differentiate into several cell types, including odontoblasts, neural progenitors, osteoblasts, chondrocytes and adipocytes. The dental stem cells exist widely in dental tissues, including dental pulp, periodontal ligament, dental papilla, and dental follicle. Technologies using dental stem cells might be a new model of renewal medicine.

关 键 词：牙源干细胞 组织工程 组织再生 

分 类 号：R780.2[医药卫生—口腔医学]