温和灸“关元”穴对慢性疲劳大鼠免疫球蛋白的影响  

Influence of Mild Moxibustion at Guanyuan Point on Immunoglobulins of Chronic Fatigue Rats

作　　者：成泽东[1] 赵奕[1] 陈以国[1] 

机构地区：[1]辽宁中医药大学,辽宁沈阳110032

出　　处：《中华中医药学刊》2013年第2期339-341,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：辽宁省自然科学基金资助项目(20102144)

摘　　要：目的:观察温和灸小肠募穴"关元"穴对慢性疲劳综合征(CFS)大鼠血清IgA、IgM、IgG含量的影响。方法:清洁级SD雌性大鼠60只,体重(170±10)g,造模7 d后,采用随机数字表法随机分成4组,每组15只。通过力竭游泳加慢性束缚法制备CFS大鼠模型,造模成功后,分别进行药物治疗和温和灸"关元"穴治疗,21 d后,采用ELISA检测各组大鼠血清IgA、IgM、IgG的含量。结果:①模型组血清IgA、IgM、IgG的含量降低,与正常组相比有显著性差异(P<0.05)。②艾灸组可使大鼠血清中血清IgA、IgM、IgG的含量增高至正常水平,与模型组相比都有显著性差异(P<0.05)。③艾灸组可使大鼠血清中血清IgA、IgM、IgG的含量增高至正常水平,与正常组相比无显著性差(P>0.05)。结论:温和灸小肠募穴"关元"穴能增高血清IgA、IgM、IgG的含量至正常水平,维持免疫功能的稳定,这可能是其抗疲劳的机制之一。Objective ：To observe the mild moxibustion at Guanyuan point on serum IgA, IgM ,IgG levels of chronic fatigue syndrome （CFS）. Method：60 clean grade SD female rats, weighing （170 ± 10 ）g,7 d after modeling, according to the random number table, were randomly divided into 4 groups of 15 in each group. Plus chronic restraint by exhaustive swimming in rats prepared by CFS model was successful, drug treatment and mild moxibustion at Guanyuan point were the treatment, lasting for 21 days and using ELISA test to detect serum levels of IgA, igM, IgG. Results ： （~ The serum levels of IgA, IgM, IgG decreased and compared with the normal group there was significant difference（P 〈 0.05）. ② moxibustion serum group can increase serum levels of IgA, IgM, IgG levels to normal levels ; and compared with model group there was significant difference （P 〈 0. 05 ）. ③ moxibustion serum group can increase serum levels of IgA, IgM, IgG levels to normal levels,and compared with the normal group there was no significant difference（P 〉0.05 ）. Conclusion： Mild moxibustion at Guanyuan point can increase serum levels of IgA, IgM, IgG to normal levels and maintain the stability of immune func- tion,which may be one of the mechanisms of its antifatigue.

关 键 词：灸 募穴 慢性疲劳综合征 IGA IGM IGG 

分 类 号：R224.2[医药卫生—中医基础理论]