综合护理干预对脑卒中后抑郁的影响  

Effects of Comprehensive Nursing Intervention on Depression of Post-stroke Patients

作　　者：李桂林[1] 费静霞[1] 冷文娟[1] 李金香[1] 徐文炜[1] 张玉琦[1] 

机构地区：[1]中国.南京医科大学附属无锡精神卫生中心,无锡214151

出　　处：《中国健康心理学杂志》2013年第1期58-60,共3页China Journal of Health Psychology

基　　金：无锡市科技计划项目(编号:CSE01N1118);无锡市医院管理中心医学技术重大项目(编号:YGZX1116)

摘　　要：目的探讨综合护理干预并舍曲林对脑卒中后抑郁状态的影响。方法将121例脑卒中后抑郁患者随机分为研究组(61例)和对照组(60例),研究组患者给予综合护理干预并舍曲林,对照组患者单纯给予舍曲林。在综合护理干预前和综合护理干预后8周分别用汉密尔顿抑郁量表(HAMD)、简易精神状态检查量表(MMSE)、临床神经功能缺顿量表(CSS)、Barthel指数(MBI)评价两组患者的疗效。结果研究组患者综合护理干预前、后HAMD、MMSE、CSS、MBI评分间差异有显著统计学意义(tHAMD=11.9050,MtMSE=-5.5822,tCSS=12.6566,MtBI=-17.9000;P均<0.001);对照组患者综合护理干预前、后HAMD、MM-SE、CSS、MBI评分间差异也有统计学意义(tHAMD=8.6587,P<0.001;MtMSE=-2.8570,P<0.01;tCSS=2.2251,P<0.05;MtBI=-2.1007,P<0.05)。综合护理干预前两组患者HAMD、MMSE、CSS、MBI评分差异无统计学意义(P>0.05),但综合护理干预后两组患者HAMD、MMSE、CSS、MBI评分差异有统计学意义(HtAMD=2.1274,P<0.05;MtMSE=4.2260,P<0.01;tCSS=9.1274,P<0.001;MtBI=16.2776,P<0.001)。结论综合护理干预并舍曲林对脑卒中后抑郁有较好效果,而且能够明显改善患者认知能力和神经功能,提高日常生活活动能力,提高生活质量。Objective To explore the effects of comprehensive nursing intervention combined sertraline on depression of post-stroke patients.Methods A total of 121 post-stroke patients with depression were randomly divided into the study group（n=61）and control group（n=60）.The study group patients were got the comprehensive nursing intervention combined sertraline and control group took sertraline.There were respectively evaluation of the efficacy of the two groups of patients using the Hamilton Depression Rating Scale（HAMD）,the Mini-Mental state Examination（MMSE）,clinical neurological lack of Dayton scale（CSS）,Barthel index（MBI）,before comprehensive nursing intervention and after comprehensive nursing intervention 8 weeks.Results After eight weeks,there were significant differences in HAMD,MMSE,CSS and MBI scores in the study group（tHAMD=11.9050,tMMSE=-5.5822,tCSS=12.6566,tMBI=-17.9000,Pall0.001）.there were also significant differences in the control group（tHAMD=8.6587,P0.001;tMMSE=-2.8570,P0.01;tCSS=2.2251,P0.05;tMBI=-2.1007,P0.05）.Before the comprehensive nursing intervention,both groups of HAMD,MMSE,the CSS,MBI scores were no significant difference（P0.05）,but there were significant differences in HAMD,MMSE,CSS,and MBI scores between two groups after eight weeks（tHAMD=2.1274,P0.05;tMMSE=4.2260,P0.01;tCSS=9.1274,P0.001;tMBI=16.2776,P0.001）.Conclusion Comprehensive nursing intervention combined sertraline has higher effect on post-stroke patients with depression;and can improve cognitive ability,nerves function,activity of daily living and quality of life.

关 键 词：脑卒中后抑郁 综合护理干预 汉密尔顿抑郁量表 简易精神状态检查量表 

分 类 号：R743.3[医药卫生—神经病学与精神病学]