普瑞巴林治疗脊髓损伤后神经病理性疼痛的疗效观察  

Efficacy of Pregabalin in Treatment of Spinal Cord Injury and Neuropathic Pain

作　　者：李雪红[1] 李伟[1] 范永春[1] 张俊[1] 

机构地区：[1]黑龙江省农垦总局总医院,黑龙江哈尔滨150088

出　　处：《中国伤残医学》2013年第2期6-7,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：观察普瑞巴林治疗脊髓损伤后神经病理性疼痛的疗效。方法：将40例脊髓损伤后伴有神经病理性疼痛的患者（治疗前VAS评分4～7分）随机分为治疗组及对照组，治疗组患者口服普瑞巴林150-300mg／d，对照组口服卡马西平0．2～0．6g／d；治疗前及治疗2周、4周后分别使用VAs（视觉模拟评分法进行评分），VAS评分降为≤2分为显效，VAS评分≤3分为有效，VAS评分≥4分为无效。结果：治疗组：显效12例，有效6例，无效2例；对照组：显效6例，有效7例，无效7例。结论：普瑞巴林能有效治疗脊髓损伤后神经病理性疼痛。Objective：To study on efficacy for neuropathic pain in the the view ofpregabalin after spinal cord injury. Methods： 40 patients with spinal cord injury patients with neuropathic pain （VAS score 4-7 before treatment） were randomly divided into a treatment group and the control group, patients treated with oral pregabalin 150-300mg/ day, the control group was treated KamaXiping 0.2-0.6g / day; reduced to ≤2 was divided into markedly, VAS score before treatment and after two weeks, four weeks, respectively, using the VAS （visual analogue scale score）, VAS score ≤ 3 divided into effective VAS score ≥4 is divided into invalid. Results：Treatment groups： 12 cases markedly effective in 6 cases, 2 cases; control group： 6 cases markedly effective in 7 cases, 7 cases. Conclusion：Pregabalin effective in the treatment of spinal cord injury and neuropathic pain.

关 键 词：脊髓损伤 神经病理性疼痛 普瑞巴林 

分 类 号：R741[医药卫生—神经病学与精神病学]