肝脏损害和腹水对纤维化扫描仪测量值的影响  

The influence of liver injury and ascites on FibroScan values

作　　者：陈林姣[1] 孔菲[1] 尹小林[1] 温晓玉[1] 牛俊奇[1] 

机构地区：[1]吉林大学第一医院肝胆胰内科,吉林长春130021

出　　处：《中国实验诊断学》2013年第2期291-293,共3页Chinese Journal of Laboratory Diagnosis

基　　金：国家自然科学基金项目(81072430)

摘　　要：目的探讨肝脏损害和腹水对慢性乙型病毒性肝炎和肝硬化患者的FibroScan(FS)的影响。方法 2009年9月至2011年1月在我院肝胆胰内科住院并行FS检查的患者。根据《慢些乙型肝炎防治指南(2010版)》及影像检查提示有无肝硬化图像及生化指标,将患者分为慢些乙型病毒性肝炎重度(A组)、中等(B组)、轻度(C组)和乙肝后肝硬化失代偿期组。再将肝硬化患者分为无腹水无肝损害组(D)、中度以上肝损害组(E组)、重度以上腹水组(F组)。计算各组的FS值的均值和标准差,进行组间t检验。结果 FS值的均值:A组>B组>C组,且组间差异具有显著性(P<0.01);E组和F组的FS值均值均明显高于D组,E组和D组间,F组和D组间均有显著差异(P<0.01)。结论肝脏损害和腹水均可导致FS值明显偏高,对FS值有影响。Objective To explore the influence o3 liver injury and ascites on FibroScan values for Chronic Hepatitis B（CHB）and cirrhosis patients. Methods Patients who have received FibroScan examine and been in our department from September 2009 to January 2011 were divided into CHB serious group （A group） ,CHB mediate group （B group） 、 CHB light group （C group） and cirrhosis of the liver decompensation period according to Guide to the prevention and control of chronic hepatitis B（2010） and if there is cirrhosis image in imaging examine. Then cirrhosis patients were clasified as without ascites and liver injury group （D group） ,Moderate or above liver injury group （E group） ,Moderate or above ascites groups （F group）. Then calculate the average and standard deviation of every group,carry out test be- tween AB,AC,BC,DE,DF groups. Results the average of FibroScan values.. A group 〉B group 〉Cgroup,the diversi- ty between these groups are remarkable（P〈0.01） ;The average of both E group and F group was higher than that of D group,there were significant differences between D and E group,between D and F group（P〈0. 01）. Conclusion both liver injury and ascites have lead to the increase of FibroScan values,and so have influence on FibroScan values.

关 键 词：肝纤维化 FIBROSCAN 肝硬化 肝炎 腹水 

分 类 号：R575.2[医药卫生—消化系统]