奥美拉唑、阿莫西林、克拉霉素三联疗法治疗十二指肠溃疡的临床疗效  

Clinical Effect of Omeprazole,Amoxicillin,Clarithromycin in Triple Therapy for the Patients with Duodenal Ulcer

作　　者：张雪芹[1] 

机构地区：[1]云南省曲靖市第一人民医院,云南曲靖655000

出　　处：《中国医学创新》2013年第3期14-15,共2页Medical Innovation of China

摘　　要：目的:探讨奥美拉唑、阿莫西林、克拉霉素三联疗法治疗十二指肠溃疡的临床疗效。方法:选取2010年9月-2012年2月于本院进行治疗的64例十二指肠溃疡患者为研究对象,将其随机分为对照组(奥美拉唑组)和观察组(奥美拉唑、阿莫西林、克拉霉素三联疗法组),每组各32例,后将两组患者的治疗总有效率、腹痛消失时间、复发率及治疗前后的血清GAS、SST、PGⅠ及PGⅡ水平进行比较。结果:观察组的治疗总有效率高于对照组,腹痛消失时间短于对照组,复发率低于对照组,治疗后血清GAS、SST、PGⅠ及PGⅡ水平均低于对照组(P<0.05)。结论:奥美拉唑、阿莫西林、克拉霉素三联疗法治疗十二指肠溃疡的临床疗效较佳。Objective： To study the clinical effect of omeprazole, amoxicillin, elarithromycin in triple therapy for the patients with duodenal ulcer.Method： 64 patients with duodenal ulcer in our hospital from September 2010 to February were selected as research object, and they were randomly divided into contro]t group （ omeprazole group ） and observation group （ omeprazole, amoxicillin, clarithromyein in triple therapy group ） with 32 cases in each group, then the total effective rate, disappeared time of abdominal pain, recurrence rate and serum GAS, SST, PG I, PG II before and after the treatment of two groups were compared. Result： The total effective rate of observation group was higher than that of control group, disappeared time. of abdominal pain was shorter than that of control group, recurrence rate was lower than that of control group, serum GAS, SST, PG Ⅰ and PG Ⅱ were all lower than those of control group （ P〈0.05 ）, there were all significant differences.Conclusion： The clinical effect of omeprazole, amoxieillin, clarithromycin in triple therapy for the patients with duodenal ulcer is better.

关 键 词：奥美拉唑 阿莫西林 克拉霉素 十二指肠溃疡 疗效 

分 类 号：R573.1[医药卫生—消化系统]