Noninvasive blood glucose measurement by ultrasound-modulated optical technique  

作　　者：朱莉莉 林洁清 林栢清 李晖 

机构地区：[1]Key Laboratory of Optoelectronic Science and Technology for Medicine of the Ministry of Education,Fujian Provincial Key Lab of Photonic Technology,College of Photonic and Electronic Engineering,Fujian Normal University

出　　处：《Chinese Optics Letters》2013年第2期68-72,共5页中国光学快报（英文版）

基　　金：supported by the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT1115);the National Natural Science Foundation of China(No.61178089);the Research Fund for the Doctoral Program of Higher Education(No.200803940001);the Research Program of Fujian Provincial Educational Department(No.JA10068)

摘　　要：We present a method for the noninvasive measurement of blood glucose levels, which are determined by the ultrasound-modulated optical technique, The method is based on the optical scattering coefficient. A sensitivity analysis of the ultrasound-modulated light signals in a scattering medium is conducted. Glucose concentrations in intralipid and hemoglobin solutions are measured using the modulation depth of ultrasound-modulated scattered light. The effects of incident light intensity and sample temperature on the ultrasound-modulated signals are also estimated. Preliminary experimental results suggest that the proposed method is a promising technique for noninvasive blood glucose measurement.We present a method for the noninvasive measurement of blood glucose levels, which are determined by the ultrasound-modulated optical technique, The method is based on the optical scattering coefficient. A sensitivity analysis of the ultrasound-modulated light signals in a scattering medium is conducted. Glucose concentrations in intralipid and hemoglobin solutions are measured using the modulation depth of ultrasound-modulated scattered light. The effects of incident light intensity and sample temperature on the ultrasound-modulated signals are also estimated. Preliminary experimental results suggest that the proposed method is a promising technique for noninvasive blood glucose measurement.

关 键 词：BLOOD Light scattering Surface plasmon resonance 

分 类 号：R312[医药卫生—基础医学] TN911.3[电子电信—通信与信息系统]