男性酒依赖患者的决策倾向研究  

The study of decision-making biases in male alcohol dependent patients

作　　者：尹良爽[1] 李泽爱[2] 朱春燕[1] 庞良俊[2] 董文文[1] 汪凯[1] 

机构地区：[1]安徽医科大学医学心理学系,合肥230032 [2]安徽省精神卫生防治中心

出　　处：《中华精神科杂志》2013年第1期28-31,共4页Chinese Journal of Psychiatry

基　　金：国家自然科学基金（31100812）;安徽省国际科技合作计划（10080703040）

摘　　要：目的探讨男性酒依赖（alcohol dependence，AD）患者认知能力的风险决策。方法将32例AD患者（患者组）与其人口学资料相匹配的正常对照（对照组）作为研究对象，采用爱荷华博弈任务（Iowa Gambling Task，IGT）进行决策能力的测试，分别应用焦虑自评量表（SAS）、抑郁自评量表（SDS）和简明智力量表（MMSE）对2组患者进行评定。结果患者组在IGT中净不利选牌数明显高于对照组[（1．38±18．01）次：（-6．34±12．10）次]，2组比较差异有统计学意义h（6.5）=2．074，P=0．042]。采用2（组）×5（阶段）方差分析比较不同阶段的净不利选牌数结果显示，2组间的主效应显著[F（1.65）=5．357，P=0．024]，不同阶段的主效应亦显著[F（4.260）=16．252，P〈0．001]；但随着博弈任务卡片选择次数的增多，2组有利选择次数均逐渐增加。AD患者净不利选牌数与初次饮酒年龄及成瘾年龄呈负相关（r=-0．541，P=0．001；r=-0．350，P=0．050）。结论男性酒依赖患者可能存在决策能力障碍。Objective To investigate the characteristics of decision-making in male patients with alcohol dependence （AD）. Methods A total of 32 male patients were compared with matched 32 normal controls on the Iowa Gambling Task. Meanwhile, all of the subjects were evaluated with the Self-Rating Anxiety Scale （SAS）, Self-Rating Depression Scale （SDS） and Mini-Mental State Examination （MMSE）. Results The AD group selected more net disadvantageous cards （number of cards selected from the disadvantageous decks minus number of cards selected from advantageous decks ） than normal controls [ （1.38 ±18. 01）times vs. （ -6.34 ±12. 10） times; t（6.5） =2.074, P=0.042].The 2（group） x5（block） ANOVA （analysis of variance ） on the cards of net disadvantageous from the gambling task revealed a significant main group effect [ F（1,65） = 5. 357 ,P = 0. 024 ] , and a significant main effect of block [ F（4,260） = 16.252, P 〈 0.001 ]. The results showed that normal controls and patients with alcohol dependence gradually shifted their selections toward the good decks as the game progresses. The total number of net disadvantageous cards in AD subjects was negatively correlated to the age of initial alcohol use and the age of addiction （r= -0.541,P=0.001;r= -0.350,P=0.050;respeetively）. Conclusion The present study suggests that the decision-making impairment might be in male alcohol dependence patients.

关 键 词：决策 情绪 酒依赖 

分 类 号：R749.62[医药卫生—神经病学与精神病学]