缺血性脑血管病患者颅外动脉狭窄与肾动脉狭窄的关系  

Relationship between extracranial artery stenosis and renal artery stenosis in patients with ischemic cerebrovascular disease

作　　者：李瑶宣[1] 董艳玲[1] 黄慧雯[1] 

机构地区：[1]广西壮族自治区人民医院神经科,南宁530021

出　　处：《临床神经病学杂志》2013年第1期61-62,共2页Journal of Clinical Neurology

基　　金：广西壮族自治区卫生厅研究项目(Z2008053)

摘　　要：目的探讨缺血性脑血管病(ICVD)患者颅外动脉狭窄与肾动脉狭窄(RAS)的关系。方法对310例ICVD患者行全脑数字减影血管造影(DSA)及肾动脉造影检查,分析颅外动脉狭窄程度及数量与RAS率的关系。结果颅外动脉重度狭窄及闭塞组的RAS率显著高于轻、中度狭窄组及无狭窄组(均P<0.01);2支及≥3支颅外动脉狭窄患者的RAS率显著高于无狭窄及1支血管狭窄的患者(P<0.05～0.01)。重度颅外动脉狭窄及闭塞、2支、≥3支颅外动脉狭窄是RAS的危险因素(OR=3.025,OR=3.343,OR=5.733;均P<0.01)。结论重度颅外动脉狭窄及闭塞、≥2支颅外动脉狭窄是ICVD患者RAS的危险因素。Objective To investigate the relationship between extracranial artery stenosis and renal artery stenosis （RAS） in patients with ischemie eerebrovascular disease （ICVD）. Methods Three hundred and ten ICVD patients were carried out digital subtractiona ngiography （DSA） and renal artery ngiography. The relationship was analyzed between the different degree and number of extracranial artery stenosis and the rate of RAS. Results The rate of RAS in extracranial artery severe stenosis and occlusion group were significantly higher than mild stenosis group, moderate stenosis group and no stenosis group （ all P 〈 0. 01 ）. The rates of RAS were significantly increased in patients with 2 vascular stenosis and ≥3 vascular stenosis than the patients with no extracranial artery stenosis and 1 vascular stenosis （P 〈0. 05-0.01 ）. Extracranial artery severe stenosis and occlusionm, patients with 2 vascular stenosis and ≥3 vascular stenosis were risk factors of RAS （ OR = 3. 025, OR = 3. 343, OR = 5. 733 ; all P 〈 0. 01 ）. Conclusions Severe stenosis and occlusionm, patients with ≥2 vascular stenosis are the risk factors of RAS.

关 键 词：缺血性脑血管病 颅外动脉狭窄 肾动脉狭窄 

分 类 号：R743.3[医药卫生—神经病学与精神病学]