乳腺癌钙化的X线表现与病理学分型分级的相关性  

The correlation between calcification breast cancer of X-ray manifestations and its pathologic classification and grading

作　　者：张曦[1] 汪湍[1] 蔡斌[1] 李莉[1] 冯成堂[1] 文智[1] 

机构地区：[1]新疆医科大学附属肿瘤医院,新疆乌鲁木齐830011

出　　处：《实用放射学杂志》2013年第2期220-224,234,共6页Journal of Practical Radiology

摘　　要：目的探讨乳腺癌钙化的x线表现与病理组织学分型分级的关系。方法收集行数字化乳腺X线摄影检查，并经手术病理证实的166例乳腺癌，对病变钙化的形态、分布、数目以及钙化和肿块关系、钙化伴有情况与病理学分型分级之间的相关性进行分析。结果导管原位癌：低级别成簇分布占71．4％（5／7）；钙化合并肿块占57．1％（4／7）；中级别钙化伴致密影占40．0％（2／5）；高级别钙化数目〉35个占77．8％（21／27）。浸润性导管癌：Ⅰ级钙化数目〉35个占50．0％（4／8）；钙化伴致密影占37．5％（3／8）；Ⅱ级钙化数目〈15个占36．8％（28／76）；钙化合并肿块占72．4%（55／76）；钙化在肿块内占44．7％（34／76）；Ⅲ级钙化成簇分布占75．0％（15／20）。结论乳腺癌不同病理分型影像学表现各有不同，根据乳腺癌钙化x线表现对其进行分型分级研究，为指导临床提供帮助。Objective To explore the correlation between calcification of breast cancer of X-ray manifestations and pathologic-his- tological classification and grading. Methods 166 cases of surgical pathologically confirmed breast cancer that were underwent digital breast radiography examination were enrolled in this study. The lesions＇ calcification form, distribution, number, the relationship between calcification and mass, as well as the correlation between calcification and pathology classification and grading. Results Duc- tal carcinoma in situ= low grade tumor with clustering calcification accounted for 71.4 %（5/7） ; calcification with mass accounted for 57.1%（4/7） ; middle grade tumor with calcification and high density accounted for 40.0% （2/5） ; there were more than 35 calcifi- cation loci at high grade tumors （77.8%, 21/27）. Infiltrating ductal carcinoma：Ⅰ level calcification number more than 35 accoun- ted for 50.0% （4/8） ; calcification with high density accounted for 37.5 %（3/8） ; Ⅱ level calcification number less than 15 accoun- ted for 36.8% （28/76） ; calcification with mass accounted for 72.4% （55/76） ; calcification in mass in 44.7% （34/76） ;Ⅲ level cal- cification fascicles distribution accounted for 75.0% （15/20）. Conclusion Different pathological type of breast cancer have different imaging findings, according to the classification and grading of breast cancer may be helpful in clinical treatment.

关 键 词：乳腺 乳腺癌 钙化 乳腺X线摄影 病理学 

分 类 号：R737.9[医药卫生—肿瘤] R814.41[医药卫生—临床医学]