鼻咽癌常规放疗中电子线L形野照射技术应用研究  

Application of electronic beam irradiation technology of L shape field in the traditional radiotherapy of nasopharyngeal carcinoma

作　　者：陈翠[1] 古模发[1] 危芬兰 张广顺[1] 张华满[1] 伍建华[1] 林承光[1] 

机构地区：[1]中山大学肿瘤防治中心放疗科华南肿瘤学国家重点实验室,广州510060 [2]江西省鹰潭市人民医院肿瘤科

出　　处：《肿瘤研究与临床》2013年第2期96-99,共4页Cancer Research and Clinic

基　　金：国家自然科学基金（81272575）;广东省科技计划-社会发展项目（20108080701015、2012A030400038）

摘　　要：目的探索一种能更好地解决鼻咽癌常规放疗中射野之间衔接问题的新方法。方法使用三维计划系统模拟鼻咽癌2D-适形放疗（CRT）或3D．CRT治疗中电子线L形野照射技术与常规放疗颈后电子线野照射技术的布野方法，进行剂量学分布比较。结果电子线L形野照射技术与颈后电子线野照射技术的靶区剂量超过6000eGy的包绕体积都达到95％以上，满足临床上肿瘤治疗的剂量需要，但颈后电子线野照射技术出现明显的剂量热点，最高剂量可达8900oGy，电子线L形野照射技术的最高剂量达7200cGy。电子线L形野照射技术的喉部高剂量范围比颈后电子线野照射技术小，前者喉部剂量超过6500cGy的体积为19．64％，后者为31．95％。结论电子线L形野照射技术在照射野之间衔接和剂量分布方面都具有较好的优势，值得临床推广应用。Objective To introduce a new way to solve the problem of field-field junction in the traditional radiotherapy of the nasopharyngeal carcinoma better. Methods Using the 3-dimentional planning system, the dose distribution of traditional radiotherapy and the electronic beam irradiation technology of L shape field for nasopharyngeal carcinoma in 2D- or 3D-CRT could be gotten. Results The dose coverage of V95 of the gross tumor volume （GTV） satisfied the clinical requirements. The highest dose in the electronic beam irradiation of L shape field was 7200 cGy, while it was 8900 cGy in the traditional way. The volume of dose that over 6500 cGy of throat was 19.64 % in the former, the latter was 31.95 %. Conclusion The electronic beam irradiation technology of L shape field is better than the traditional radiotherapy in field-field junction and in dose distribution. Since that, the electronic beam irradiation technology of L shape field is worth of application for the treatment of nasopharyngeal carcinoma.

关 键 词：鼻咽肿瘤 放射治疗 计算机辅助 电子线L形野照射技术 

分 类 号：R739.63[医药卫生—肿瘤]