关于喉癌患者临床手术治疗的研究  

Study on Clinical Treatment of Patients with Laryngeal Squamous Cell Carcinoma

作　　者：王静[1] 李振东[1] 

机构地区：[1]辽宁省肿瘤医院头颈外科,辽宁沈阳110042

出　　处：《世界最新医学信息文摘》2012年第10期80-81,共2页World Latest Medicine Information Electronic Version

摘　　要：目的对120例喉部分切除、喉功能重建的喉癌患者的临床资料进行回顾性分析，并对各种术式和修复方法的疗效进行评价。方法对120例喉癌患者行喉部分切除术，同期采用颈前带状肌肌筋膜瓣、会厌瓣加双蒂肌筋膜瓣和舌骨肌瓣修复喉组织缺损，重建喉功能。36例颈淋巴结转移者同期行颈廓清术。结果所有患者于术后10～15d开始进食；术后拔除气管套管率74．17％；21例发生术后感染，5例发生咽瘘；3年、5年生存率分别为75．00％和67．50％；有颈淋巴结转移者生存率低于无转移者，未接受放疗者生存率低于术后放疗者，差异均有统计学意义（P〈O．05）。结论依据喉癌发生的部位和累及范围选择不同的术式和修复方法，可提高同期喉功能重建成功率，提高患者的生活质量。Objective On 120 cases of partial laryngectomy and laryngeal function reconstruction in laryngeal carcinoma patients： a clinical retrospective analysis of data, and an evaluation of the therapeutic effect of various modes of operation and repair, Methods On 120 cases of patients undergoing resection of partial laryngectomy in laryngeal cancer, compared with an- terior cervical muscle fascia flap or Zoster epiglottic flap and bi-pedicle muscle fascia flap and hyoid muscle flaps for reconstruc- tion of laryngeal defect and reconstruction of laryngeal function. 36 cases of cervical lymph node metastasis in neck dissection over the same period. Results All patients Yu operation Hou 10~15 d began eating; operation Hou extraction tracheal casing rate 74.17%; 21 cases occurred operation Hou infection, 5 cases occurred pharyngeal fistula; 3 years, and 5 years survival rate respectively for 75% and 67.5%; has neck lymph nodes transfer who survival rate below no transfer who, is not accept radio- therapy who survival rate below operation Hou radiotherapy who, differences are has statistics significance （ P〈0.05 ）. Con- elusion Based on laryngeal carcinoma involving the range selection and location of different methods of operation and repair, improves the laryngeal function reconstruction success rates over the same period, improve the patient＇ s quality of life.

关 键 词：喉肿瘤 喉切除术 外科皮瓣 

分 类 号：R[医药卫生]