肠内普通营养与肠内免疫营养对胃癌患者术后营养支持效果比较分析  

The comparative analysis of enteral ordinary nutrition and enteral immune nutrition in postoperative nutritional support to the gastric cancer patients

作　　者：陈帆[1] 朱宏亮[1] 钱洪军[1] 

机构地区：[1]解放军第94医院普外科,江西南昌330002

出　　处：《现代预防医学》2013年第5期825-827,共3页Modern Preventive Medicine

摘　　要：目的比较肠内普通营养与肠内免疫营养对胃癌患者术后营养支持效果。方法选择2008年1月～2011年12月期间某院外科住院需要行手术治疗的30例胃癌患者作为研究对象,按照单盲数字表格法随机分组分为肠内普通营养组(TEN组)及肠内免疫营养组(EIN组)各15例,术后TEN组给与肠内普通营养,EIN给与肠内免疫营养,检测术后d1、d9患者营养指标及免疫指标变化。结果 (1)术后d1血清总蛋白、白蛋白、前白蛋白及转铁蛋白浓度在TEN与EIN组间比较差异无统计学意义(P﹥0.05),术后d9血清总蛋白、前白蛋白浓度在TEN与EIN组间比较差异有统计学意义(P﹤0.05),白蛋白及转铁蛋白组间比较差异无统计学意义(P﹥0.05)。(2)术后d1IgG、IgA、IgM、CD3、CD4、CD8在TEN与EIN组间比较差异无统计学意义(P﹥0.05),术后d9IgG、IgA、IgM、CD3、CD4在TEN与EIN组间比较差异有统计学意义(P﹤0.05),CD8组间比较差异无统计学意义(P﹥0.05)。结论肠内免疫营养较肠内普通营养对机体免疫功能上调能力更强,特定的免疫增强剂有效的保护和改善了患者免疫功能。OBJECTIVE To compare the postoperative nutritional support between enteral ordinary nutrition and enteral im- mune nutrition to the gastric cancer patients. METHODS This study included 30 gastric cancer patients who needed operation in our hospital from January 2008 to December 2011. According to the single-blind digital form method, the patients were ran- domly divided into enteral ordinary nutrition group （EON group） and enteral immune nutrition group （EIN group）. The EON group had 15 cases who were provided with enteral ordinary nutrition after the operation. The EIN group had 15 cases who were provided with enteral immune nutrition after the operation. Changes in nutritional indexes and immune indexes ld, 9d after the operation were recorded. RESULTS （1） One day after the operation, serum total protein, albumin, prealbumin and transfer- fin concentration were not significantly different between two groups （P 〉 0.05）. Nine days after the operation, serum total pro- rein, albumin concentration were significantly different between the two groups （P 〈 0.05）, but albumin and transferrin were not different between the two groups （P〉 0.05）. （2） One day after the operation, IgG, IgA, IgM, CD3, CD4, CD8 were not significantly different between the two groups （P〉 0.05）. Nine days after the operation, IgG, IgA, IgM, CD3, CD4 were significantly different between the two groups （P 〈 0.05）, and CD8 was not significantly different between the two groups （P 〉 0.05）. CONCLUSION As compared to enteral ordinary nutrition, enteral immune nutrition has a better ability to increase im- mune function and has specific immune reinforcing agent to effectively protect and improve the immune function of patients.

关 键 词：胃癌 肠内普通营养 肠内免疫营养 营养支持 

分 类 号：R735.2[医药卫生—肿瘤]