组织结构声学定量技术在肝脏弥漫性病变中的应用价值  

Diagnostic value of acoustic structure quantification technology in diffuse liver diseases

作　　者：王云忠[1] 王学梅[1] 李银燕[1] 欧国成[1] 

机构地区：[1]中国医科大学附属第一医院超声科,辽宁省沈阳市110001

出　　处：《世界华人消化杂志》2013年第5期448-453,共6页World Chinese Journal of Digestology

摘　　要：目的:探讨组织声学定量技术(acoustic structu-re quantification,ASQ)在不同程度均匀性脂肪肝及慢性乙型肝炎的诊断价值.方法:应用ASQ技术对158例正常人、139例均匀性脂肪肝患者(轻度46例,中度64例,重度29例)及66例慢性乙型肝炎患者(肝功正常43例,肝功异常23例)的肝脏进行组织声学结构定量分析,比较ASQ定量参数:众数、均值、标准差及蓝红曲线下面积比.结果:5组人群中红蓝曲线走形及曲线下面积不同;ASQ彩色编码图中,正常人组、脂肪肝组及慢性乙型肝炎组在图像上表现不同;红线Mode值在正常组与轻中重度脂肪肝组比较中有显著性差异(113.71±4.50vs111.18±2.01,104.51±2.55,97.25±2.22,P<0.01),蓝线Average、SD值在正常组、中重度脂肪肝组与慢性乙型肝炎组有显著差异(P<0.01),红线Average值、SD值及RB Ratio值在3组人群中有显著性差异(P<0.01);红线Mode值、Average值及RB Ratio值在慢性乙型肝炎肝功正常组及异常组比较中有显著性差异(P<0.05).结论:ASQ定量参数值可以在一定程度上间接反映均匀性脂肪肝的严重程度.To assess the diagnostic value of acoustic structure quantification （ASQ） technology in ho mogeneous fatty liver and chronic hepatitis B. METHODS： One hundred and fifty-eight normal subjects, 139 patients with homogeneous fatty liver disease （46 mild cases, 64 moderate cases and 29 severe cases） and 66 patients with chronic hepatitis B （43 cases with normal and 23 cases with abnormal liver function）, who underwent quantitative assessment of liver tissue using the ASQ technology, were included in the study. ASQ quantitative parameters were compared among different groups, including mode, mean, standard deviation （SD）, and the ratio of blue to red （RB ratio） color histogram curve area.RESULTS： Red and blue curves were different in shape and area under the curve among the five groups. The normal group, fatty liver group and chronic hepatitis B group were different in ASQ color coding graph. The redline mode value had a significant difference between the normal group and fatty liver group （113.71±4.50 vs 111.18 ±2.01, 104.51 ±2.55, 97.25 ＋ 2.22, all（ P 〈 0.01）. The blueline mean and SD values in the normal group, moderate to severe fatty liver group and chronic hepatitis B group also had significant difference （all P 〈 0.01）. There were significant differences in redline mean, SD and RB ratio values among the three groups （P 〈 0.01）. The redline mode value, mean value and RB ratio had significant differences between the normal and abnormal liver function groups in patients with chronic hepatitis B （all P 〈 0.05）. CONCLUSION： ASQ quantitative parameters can indirectly reflect the severity of homogeneous fatty liver to a certain extent.

关 键 词：超声 组织声学定量技术 脂肪肝 慢性乙型肝炎 

分 类 号：R575[医药卫生—消化系统]