小梁切除手术对眼表的影响  

The impact of trabeculectomy on ocular surface

作　　者：李璐希[1] 刘伟[1] 季建[1] 

机构地区：[1]天津医科大学眼科医院,300384

出　　处：《中华眼科杂志》2013年第2期185-188,共4页Chinese Journal of Ophthalmology

摘　　要：青光眼是不可逆性致盲眼病之一。目前小梁切除术仍是最常用的手术治疗方式，其手术区功能性滤过泡的形成是手术成功的主要标志。但有多项研究结果显示，青光眼患者行小梁切除术后，其术眼的泪膜成分和功能发生了变化，导致术眼的眼表结构和舒适度改变，甚至发生干眼症。多数研究者认为小梁切除术对眼表的损害与手术中联合使用抗代谢药物、术后滤过泡隆起度高或形成薄壁无血管的滤过泡密切相关。Glaucoma is an eye disease that can lead to irreversible visual impairment. Trabeculectomy remains the most common operation for glaucoma therapy. The formation of functional filtering bleb is the key to the success of surgery. But many studies have found that anti-glaucoma surgeries affected the normal function of the tear film, which can cause the change of the structure of ocular surface resulting in an uncomfortable feeling and dry eye. Most investigators have suggested that the alteration of ocular surface by trebulectomy is due partially to the damage of ocular surface tissues and topical application of the drugs of antimetabolism as well as the lack of vascular supply of ultra-thin post-operative filtering bleb.

关 键 词：青光眼 小梁切除术 泪器 水疱 

分 类 号：R779.6[医药卫生—眼科]