宫颈癌根治术后常规放射治疗与三维适形放射治疗的临床观察  

A clinical comparative study between conventional radiotherapy and three-dimensional conformal radiotherapy for cervical cancer

作　　者：任锦霞[1] 赵林[1] 吉宏[2] 刘爱荣[1] 罗莉[1] 

机构地区：[1]甘肃省肿瘤医院放疗科,甘肃兰州730050 [2]甘肃省肿瘤医院妇瘤科,甘肃兰州730050

出　　处：《兰州大学学报（医学版）》2012年第3期61-64,共4页Journal of Lanzhou University（Medical Sciences）

基　　金：甘肃省科技厅科技支撑计划项目(090NKCA091)

摘　　要：目的探讨三维适形放疗在宫颈癌根治术后治疗的可行性及临床优势。方法选取90例宫颈癌患者,其中观察组46例为三维适形放疗组,对照组44例为常规放射治疗组,综合评价两种治疗方案的临床疗效、治疗副反应、生存质量等。结果两组1、2年生存率及局部控制率均为100%,观察组的直肠反应、膀胱不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论三维适形放疗与常规放疗治疗宫颈癌的近期疗效相近,但三维适形放疗明显降低了直肠、膀胱反应的发生率及严重程度,明显改善了患者的生存质量。Objective To investigate the radical feasibility and clinical advantages of three-dimensional conformal radiotherapy in treating cervical cancer.Methods 90 cases of cervical cancer were selected and they were divided into observation group with 46 cases for three-dimensional conformal radiotherapy and control group with 44 for conventional radiotherapy.A comprehensive evaluation was made to judge the clinical efficacy,treatment side effects,quality of life and etc for two treatment options.Results The 2-year survival and local control rates for both groups were 100%.But there were difference in adverse reactions：the observation group＇s response rates to the rectum,bladder reaction were lower than those of the control group,and the difference was statistically significant（P0.05）.Conclusion Although the overall curative effect between three-dimensional conformal radiotherapy and conventional radiotherapy is similar and has no difference in statistically significance,the treatment of the former can reduce the incidence of rectal and severity of reaction,and can improve the patients＇ quality of life.

关 键 词：宫颈癌 三维适形放疗 常规放疗 临床观察 

分 类 号：R737.33[医药卫生—肿瘤]