奥拉西坦联合三七通舒治疗血管性痴呆的临床疗效观察  

Observation on Clinical Effects of Oxiracetam Capsule and SanQi TongShu Capsule in Treating Vascular Dementia

作　　者：李伟伟[1] 王鸣池[2] 于盼盼[1] 王悦[1] 

机构地区：[1]天津中医药大学,天津300037 [2]天津市南开医院

出　　处：《西部中医药》2013年第2期81-83,共3页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察奥拉西坦联合三七通舒治疗血管性痴呆的临床疗效。方法:将60例血管性痴呆患者随机分为治疗组和对照组各30例,对照组给予奥拉西坦胶囊0.8 g/次,3次/d,口服,治疗组在对照组治疗的基础上加用三七通舒胶囊0.2 g/次,3次/d,口服,疗程均为12周。计算治疗前、后Fl st ei n简易精神状态检查量表(MMSE)、临床痴呆程度量表(CDR)、日常生活评定量表(ADL)、神经功能缺损量表(NIHSS)评分。结果:治疗前2组各项指标评分比较差异无统计学意义(P>0.05),治疗前后及治疗后2组各项指标评分比较差异有统计学意义(P<0.05)。结论:奥拉西坦联合三七通舒能明显改善血管性痴呆患者的认知功能,提高日常生活能力,改善神经损伤。Objective： To observe clinical effects ofoxiracetam capsule and SanQi TongShu capsule in treating vascular dementia. Method： Sixty patients were randomly divided into the treatment group and the control group equally. The control group took oxiracetam capsule, 0.8g each time, three times each day. Based on the treatment given to the control group, the treatment group also took SanQi TongShu capsule, 0.2g each time, three times each day. One course of treatment was 12 weeks. The scales ofMMSE, CDR, ADL and NIHSS were calculated before and after treating. Result： The differences of comparisons between both groups before treating had no statistical meaning in indicators （P〉0.05）. The differences of comparisons between both groups demonstrated statistical meaning in indexes before and after treating （P〈0.05）. Conclusion： Oxiracetam capsule and SanQi TongShu capsule could improve cognitive function, activity of daily living and nerve damage of patients with vascular dementia.

关 键 词：血管性痴呆 奥拉西坦胶囊 三七通舒胶囊 临床疗效 

分 类 号：R749.13[医药卫生—神经病学与精神病学]