多效唑暴露对褐菖鮋脾脏抗氧化防御系统的影响  

Effects of Paclobutrazol Exposure on Antioxidant System of Fish Spleen

作　　者：李进寿[1,2] 阮俊峰[2] 耿宏[1] 王重刚[1] 

机构地区：[1]厦门大学近海海洋环境科学国家重点实验室,福建厦门361005 [2]宁德师范学院生物学系,福建宁德352100

出　　处：《厦门大学学报（自然科学版）》2013年第2期267-272,共6页Journal of Xiamen University：Natural Science

基　　金：高等学校博士学科点专项科研基金资助课题(20100121110005);福建省自然科学基金项目(2012D114);宁德师范学院服务海西建设基础重点项目(2011H309)

摘　　要：多效唑是农业上使用广泛的三唑类杀菌剂和植物生长调节剂,但很少有研究涉及到多效唑对鱼类的毒理学效应.以环境相关质量浓度(10,100,1000ng/L)的多效唑对褐菖鮋(Sebastiscus marmoratus)进行50d的水体暴露,检测多效唑对褐菖鮋脾脏抗氧化防御系统指标的影响.结果显示,褐菖鮋脾脏的谷胱甘肽(GSH)、谷胱甘肽-S-转移酶(GST)、谷胱甘肽过氧化物酶(GSHPx)、丙二醛(MDA)和Na+-K+-ATPase等相关指标在多效唑毒性作用下都出现了相应的变化,且这些变化与多效唑呈剂量-效应关系.表明多效唑的暴露对褐菖鮋的抗氧化防御系统的功能造成了损伤.实验的结果说明,多效唑等唑类农药的长期使用对鱼类等水生生物和水体环境造成了生态压力.Paclobutrazol （PBZ） is widely used as triazole fungicide and plant growth regulator in agriculture.But the toxicology of PBZ on fishes was seldom studied.This research was designed to detect the influence of PBZ on the spleen antioxidant system of Sebastiscus marmoratus that was exposed at an environmental concentration of PBZ （10,100,1 000 ng/L） for 50 d.The result showed that the glutathione （GSH）,glutathione-S-transferases （GST）,glutathione peroxidase （GSHPx）,malondialdehyde （MDA）,and Na＋-K＋-ATPase of spleen were presented with a concentration dependence variation under the action of PBZ,which indicated the exposure of PBZ had harmful to the antioxidant system of Sebastiscus marmoratus.The result showed that long-term usage of PBZ may cause ecological pressure on aquatic organisms such as fishes and aquatic environment etc.In view of the long-term use of pesticides that may lead to environmental problems,it is necessary to carry out the researches that pesticides have toxicogenic effect on fishes and Marine organisms.This study has actual significance for the protection,estimate and monitor of the ocean ecological environment.

关 键 词：褐菖鮋 多效唑 抗氧化防御系统 

分 类 号：X174[环境科学与工程—环境科学]