健脾化痰法治疗老年性痴呆痰浊阻窍证的疗效及机制研究  

Efficacy and mechanism research on treating phlegm blocking orifices symptoms from senile dementia by Jianpi Huatan therapy

作　　者：王清峰 张丹 李柱 

机构地区：[1]开封市中医院,河南开封475000

出　　处：《中医临床研究》2013年第2期12-13,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨健脾化痰法治疗老年性痴呆痰浊阻窍证的疗效及机制。方法:门诊及住院老年性痴呆痰浊阻窍证患者120 例采用单纯随机分组设计随机分为试验组和对照组各 60 例,试验组运用健脾化痰法治疗,对照组运用吡拉西坦片治疗。结果:经过观察,试验组的总有效率明显高于对照组(P<0.05)。治疗前两组中医证候积分对比无明显差异,治疗后两组对比差异明显(P<0.05)。两组治疗前后 MMSE 积分都有明显上升(P<0.05),不过试验组上升幅度更大(P<0.05)。结论:健脾化痰法治疗老年性痴呆痰浊阻窍证疗效明显,也能降低胆固醇含量,值得临床推广应用。Objective： To investigate the efficacy and mechanism of treating phlegm blocking orifices symptoms from senile dementia by Jianpi Huatan therapy. Methods： 120 patients with phlegm blocking orifices symptoms from senile dementia were randomly divided into two groups, 60 patients in each group. The experimental group was given Jianpi Huatan therapy, while the control group was treated with Piracetam tablets. Results： After treatment, the total effective rate in the experimental group was significantly higher than that in the control group （P〈0.05）. No significant differences were detected between the symptom scores of two groups before the treatment, while significant differences were detected after the treatment （P〈0.05）. MMSE scores before and after treatment significantly increased （P〈0.05）, however, the experimental group was much more significant （P〈0.05）. Conclusion： Jianpi Huatan therapy was effective in treating phlegm blocking orifices symptoms from senile dementia, significantly reducing the content of cholesterol, worth a wide clinical application.

关 键 词：健脾化痰法 老年性痴呆 痰浊阻窍证 洗心汤 

分 类 号：R749.16[医药卫生—神经病学与精神病学]