原发性粒细胞肉瘤误诊1例及文献复习  

1 Case of Primary Granulocytic Sarcoma Misdiagnosis and the Literature Review

作　　者：刘松涛[1] 杨凌志[2] 

机构地区：[1]首都医科大学附属北京佑安医院重症肝病科,北京100069 [2]首都医科大学附属北京友谊医院血液科,北京100050

出　　处：《医学综述》2013年第4期765-766,共2页Medical Recapitulate

摘　　要：目的分析病例和复习文献提高对原发性粒细胞肉瘤(PGS)的临床病理特征、诊断和治疗的认识。方法回顾性分析1例PGS患者的临床资料并复习相关文献。结果 PGS以局部孤立性肿物为首发表现,病理显示核仁小,髓过氧化物酶(MPO)阳性有重要诊断意义。结论 PGS由于临床少见,诊断主要依靠免疫组织化学,尤其是对于MPO阳性者,必要时可加做髓系相关抗原,明确治疗方法与急性髓系白血病相似。Objective To improve understanding of the clinical and pathological features, diagnosis and treatment of primary granulocytic sarcoma（PGS） through analyzing cases and literature review. Methods 1 case of PGS was studied retrospectively of clinical characteristics,and related literatures were reviewed. Re- suits The initial presentation of PGS was local isolated tumor. The pathology showed that the nucleolus was small,myeloperoxidase（MPO）-positive had great diagnostic significance. Conclusion Immunohistochemis- try is the main diagnostic tool because the primary granulocytic sarcoma was rare. Especially when the MPO is positive, the myeloid-associated antigen can be added for diagnosis. Treatment of PGS is similar to that of a- cute myeloid leukemia.

关 键 词：粒细胞肉瘤 尤文肉瘤 诊断 治疗 

分 类 号：R733.71[医药卫生—肿瘤]