55例克罗恩病住院患者临床特点分析  

Analysis of the clinical characteristics of 55 patients with Crohn's disease

作　　者：郑梅英[1] 王承党[1] 庄则豪[1] 李文清[1] 陆岽[1] 

机构地区：[1]福建医科大学附属第一医院消化内科(福建医科大学消化系疾病研究室),福建福州350005

出　　处：《胃肠病学和肝病学杂志》2013年第3期257-259,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的回顾性分析克罗恩病(CD)患者的临床特点,提高对本病的认识。方法对55例确诊的CD住院患者的临床表现、实验室检查、内镜及组织病理学表现、CT/MRI影像学资料等进行统计学分析。结果 55例CD患者,男35例,女20例,年龄9～79岁,平均年龄(41.4±16.7)岁,其中10～30岁占30.91%,40～60岁占49.09%。病程1 d～13年(中位病程10.4个月)。小肠病变32例(58.18%)、回-结肠多发病变13例(23.64%)、大肠病变10例(18.18%)。最常见的症状是腹痛33例(60.00%)、大便异常28例(50.91%)。23例(41.82%)患者有肠外表现或肠外伴发病,17例(30.91%)出现肠梗阻等并发症。24例接受肠道CT或MRI检查的患者中19例有阳性发现。18例(32.1%)误诊。结论 CD缺乏特异性表现,容易误诊,需认真鉴别,显像清晰的肠道CT或MRI可以提供比较丰富的信息。Objective To identify the main clinical characteristics of Crohn＇ s disease （CD）. Methods The clini- cal features, laboratory findings, endoscopic and histological manifestations, CT/MRI imaging were investigated retro- spectively in 55 CD patients. Results 55 patients （male 35, female 20） with a mean age of （41.4 _＋ 16.7） years old and a median coure of 10.4 monthes were included in this study. The CD lesion located at the small intestine in 32 （58.18%） patients, and at the colon in 10 （ 18.18% ） patients, 13 （23.64%） patients had multiple ileocolonic le- sions. The common symptoms in CD patients were abdominal pain （60.00%） , and bowel dysfunction （50.91%）. 23 （41.82%） patients had extra-intestinal manifestations, and 17 （30.91%） intestinal obstruction. Of 24 cases received CT or MRI scan, 19 showed positive results. 18 （32.1%） patients were misdiagnosed. Conclusion The CD patients usually showed no specific manifestations, and were easily misdiagnosed. Bowel CT/MRI scans may provide more useful informations for its diagnosis.

关 键 词：克罗恩病 CT MRI影像学 病理组织学 临床特征 

分 类 号：R574.62[医药卫生—消化系统]