小牛血清去蛋白注射液防治鼻咽癌放疗不良反应的疗效观察  

Clinical observation of deproteinised calf blood serum injection on radioactive adverse reaction in patients with nasopharyngeal carcinoma

作　　者：张小玉[1] 李迎春[1] 任丽[2] 王卓敏[1] 何兰兰[1] 陈成宏[1] 钟国成[3] 

机构地区：[1]解放军第452医院核医学科,四川成都610021 [2]解放军第452医院放疗科,四川成都610021 [3]解放军第452医院肿瘤科,四川成都610021

出　　处：《现代肿瘤医学》2013年第3期512-515,共4页Journal of Modern Oncology

摘　　要：目的:研究小牛血清去蛋白注射液(DCBSI)对鼻咽癌放疗不良反应的临床疗效。方法:选择诊断明确的鼻咽癌患者72例,随机分为两组:对照组36例,给予放疗及常规护理;小牛组36例,除接受与对照相同的治疗外,还给予静脉滴注DCBSI,比较两组放疗不良反应,免疫状态及生活质量(QOL)。结果:小牛组患者的放射性皮肤损伤情况明显好于对照组,治疗后小牛组患者的免疫状态、疼痛评分及QOL均优于对照组(P<0.05)。结论:DCBSI能减轻皮肤放射性损伤,促进创面愈合,提高放疗患者的免疫状态和QOL。Objective：To study the clinical effect of deproteinised calf blood serum injection （DCBSI） to prevent and cure radioactive adverse reaction of patients with nasopharyngeal carcinoma. Methods： All 72 patients with naso- pharyngeal carcinoma were divided into two groups randomly. Control group with 36 patients were treated by radiother- apy, calf group with 36 patients were treated with radiotherapy combined with DCBSI. Then, the radioactive adverse re- action,immunologic function and quality of life （QOL） between the two groups were compared. Results： The symp- toms of skin reaction in control group were more serious than calf group; After radiotherapy, the immune functions, score of visual analogue scale and QOL in calf group were better than control group（P 〈 0. 05）. Conclusion： DCBSI can effectively relieve radioactive adverse reaction,promote skin healing and improve the immune functions and QOL of patients with nasopharyngeal carcinoma after radiotherapy.

关 键 词：小牛血清去蛋白注射液 鼻咽癌 放射治疗 不良反应 

分 类 号：R739.63[医药卫生—肿瘤]