儿童甲状腺乳头状癌临床病理观察  

Analysis of clinicopathological features and prognosis of papillary thyroid carcinoma in children

作　　者：王凤华[1] 常占平[2] 王殿军[3] 宋晶莹[1] 周颖[1] 

机构地区：[1]解放军第309医院病理科,北京100091 [2]中国航天科工集团七三一医院病理科,北京100074 [3]解放军总医院病理科,北京100853

出　　处：《现代肿瘤医学》2013年第3期515-517,共3页Journal of Modern Oncology

摘　　要：目的:探讨儿童甲状腺乳头状癌的临床病理特点、预后相关因素。方法:回顾性总结12例儿童甲状腺乳头状癌(≤14岁)的临床病理特征及预后。结果:本组12例经组织学检查证实为甲状腺乳头状癌,其中3例为术前穿刺诊断,全部行术中冰冻检查,12例均行手术切除治疗,手术时伴淋巴结转移者7例,被膜有浸润者5例。术后平均随访47.3个月,有5例复发,复发病例中2例伴肺转移,伴肺转移中有1死亡病例。结论:儿童甲状腺乳头状癌经手术治疗预后较好。术中病理冰冻切片诊断是确诊甲状腺乳头状癌的最佳方法。Objective ：To investigate the clinicopathological features and prognosis of papillary thyroid carcinoma （PTC） in children. Methods：The clinicopathological characteristics were analyzed in 12 cases of PTC in children（ 〈 14 years old）. Results：All 12 patients were confirmed as PTC by pathological examination. 3 cases were confirmed by core needle biopsy before operation and 12 cases were confirmed by frozen section during operation. All patients un- derwent surgical treatment and 7 cases with lymph node metastasis and 5 cases with capsule invasion. The average postoperative follow - up was about 47.3 months. 11 patients survived, and 5 cases had local recurrence after surgery. Conclusion：The papillary thyroid carcinoma in children can be cured through curative resection. Frozen section dur- ing operation is the best way in diagnosis of the papillary thyroid carcinoma.

关 键 词：儿童 甲状腺乳头状癌 临床病理 预后 

分 类 号：R736.1[医药卫生—肿瘤]