大剂量碘油栓塞治疗肿块型肝癌的疗效分析  

Clinical efficacy of large dose of lipiodol embolism on patients with mass hepatocellular carcinoma

作　　者：毛景松[1] 梁茂全[2] 苏洪英[2] 

机构地区：[1]沈阳市第五人民医院放射科,辽宁沈阳110001 [2]中国医科大学附属第一医院放射科介入病房,辽宁沈阳110001

出　　处：《现代肿瘤医学》2013年第3期588-591,共4页Journal of Modern Oncology

摘　　要：目的:探讨大剂量碘油介入治疗肿块型肝癌的疗效。方法:根据注入碘油剂量的不同,把符合纳入标准的肿块型肝癌病例分成两组,比较两组碘油沉积情况、术后甲胎蛋白的变化情况及生存率。结果:A组(大剂量组)碘油沉积情况优于B组(常规剂量组),以密实型沉积为主;甲胎蛋白下降所占百分数优于B组,碘油沉积与甲胎蛋白下降呈正相关。1、2、3年生存率分别为70.8%、26.2%及7.7%,高于B组生存率,两组在统计学上存在差异。两组化疗栓塞术后不良反应无统计学差异。结论:大剂量碘油介入治疗肿块型肝癌的疗效优于常规剂量。Objective：To evaluate the effect of large dose of lipiodol treatment in mass hepatocellular carcinoma （HCC） via injecting from hepatic artery in transarterial chemoembolization（TACE） case. Methods： According to the injecting dosage of lipiodol, the patients with the mass HCC were divided into two groups and compare the situation of deposit of lipiodol , the variation of - fetoprotein（AFP） after TACE and survival rate. Results： The deposit of lipiodol of group A is superior to group B（the dense type is the main one）. The decline of AFP of group A was superior to group B. The survival rates of 1,2 ,and 3 - year of group A were 70.8% ,26.2% and 7.7% respectively,which were superior to those of group B. There was no significant difference between two groups in side effects of TACE. Conclu- sion： The effect of large dose lipiodol treatment on mass hepatocellular carcinoma is superior to the common dose.

关 键 词：碘油 肝细胞癌 化疗栓塞 甲胎蛋白 

分 类 号：R735.7[医药卫生—肿瘤]