肺癌影像引导放疗图像配准标记点的研究  

Analysis to define appropriate marker of images-matching for lung cancer in IGRT

作　　者：郝春成[1] 葛晓峰[1] 徐向英[1] 卢姗[1] 云惟康[1] 刘莉莉[1] 

机构地区：[1]哈尔滨医科大学附属第三医院放疗科,黑龙江哈尔滨150040

出　　处：《现代肿瘤医学》2013年第3期622-624,共3页Journal of Modern Oncology

基　　金：黑龙江省卫生厅课题基金(编号:2012-651);哈尔滨医科大学附属第三医院科研启动基金(编号:JJ2010-19)

摘　　要：目的:探讨非小细胞肺癌影像引导放射治疗时图像匹配的参考标记点。方法:8例非小细胞肺癌患者均应用影像引导技术进行三维适形放疗或调强放疗。放疗前进行锥形束CT扫描,并将锥形束CT图像与计划CT图像分别以胸椎、隆突、肿块为标记点进行图像匹配,根据配准调整治疗床,分别记录各个方向上平移矢量,分析摆位误差。结果:8例患者共计160组配准数据,胸椎组的摆位误差最小,隆突组居中,肿块组摆位误差最大。结论:肺癌图像引导放疗图像配准的标记点选择建议使用胸椎,可选择隆突,但不推荐肿块为图像配准的标记点。Objective：To estimate the appropriate marker for the images -matching of lung Cancer IGRT. Meth- otis： Eight non- small cell lung cancer patients under went 3DCRT or IMRT. kV - CBCT scans were acquired on couch before radiotherapy. The analysis of these images was performed by automatic and manual registration of the kV - CBCT and planning CT images. The patient setup was then coizected by moving the couch accordingly. CBCT on- line - guided correction data were recorded. Results： A total of 160 CBCT sets of 8 non - small cell lung cancer pa- tients were analyzed. The errors were the smallest, mean and the biggest with ＇thoracic spine ,eminence and tumor itself as a marker, respectively. Conclusion： For IGRT image registration in three - dimensional conformal radiotherapy in lung cancer, the thoracic spine is recommended as a marker;it is possible to choose eminence as a marker;the tumor itself is not recommended as a marker.

关 键 词：肺癌 影像引导放疗 图像配准 

分 类 号：R734.2[医药卫生—肿瘤]