新西兰大白兔脑血管造影：脑底动脉环的解剖与变异  

The anatomy and variations of Willis' circle in New Zealand white rabbits: an experimental study with cerebral angiography

作　　者：杨飞[1] 姜建威[1] 王鹏[1] 吴震海[1] 成岗[1] 顾琛[1] 黄秋菊[1] 

机构地区：[1]无锡南通大学第三附属医院放射科,214041

出　　处：《介入放射学杂志》2013年第3期216-218,共3页Journal of Interventional Radiology

基　　金：无锡市医院管理中心医学科技发展基金资助(YGM1125)

摘　　要：目的研究新西兰大白兔脑底动脉环(Willis环)影像解剖与变异。方法采用介入方法,通过新西兰大白兔股动脉将微导管导入颈内动脉近端造影,分析新西兰大白兔脑底动脉环的影像解剖与变异。结果新西兰大白兔具有完整脑底动脉环,其特点是后交通动脉发达。新西兰大白兔脑底动脉环存在不同程度变异,可以分为三种类型,分别为发育不良、数目异常和异常连接。数目异常中双大脑中动脉又可分为两种亚型,共干型和分离型。结论兔脑底动脉环存在较多变异,了解兔脑底动脉环的解剖及变异对脑梗死模型的制作具有重要指导意义。Objective To study the anatomy and variations of Willis＇ circle in New Zealand white rabbits by using cerebral angiography. Methods With the help of interventional technique, catheterization of internal carotid in New Zealand white rabbits was carried out. A microcatheter was inserted via femoral artery access to the proximal site of the internal carotid, which was followed by cerebral angiography. The angiographic findings concerning the anatomy and the variations of Willis＇ circle were analyzed. Results New Zealand white rabbits had intact Willis＇ circle, and its posterior communicating artery was very prominent. Different degrees of variation in Willis＇ circle could be found in New Zealand white rabbits, which could be classified into three patterns： dysplasia, abnormality in vessel number and abnormal connection. In abnormal vessel number group, the abnormality of duplicate middle cerebral artery could be subdivided into common stem subtype and separation subtype. Conclusion The Willis＇ circle of New Zealand white rabbits has many variations. Full understanding of these variations is of great importance in guiding the preparation of cerebral infarction model.

关 键 词：脑梗死 脑底动脉环 解剖 新西兰大白兔 

分 类 号：R743.3[医药卫生—神经病学与精神病学]