植物芪类合成途径相关酶、基因和调控机制研究进展  

Relevant Enzymes,Genes and Metabolic Regulation in Biosynthesis Pathway of Stilbenes

作　　者：陆娣[1,2] 朱宽鹏[3] 夏晚霞[3] 赵树进[1,3] 

机构地区：[1]广州军区广州总医院药学部,广东广州510010 [2]南方医科大学,广东广州510515 [3]华南理工大学生物科学与工程学院,广东广州510006

出　　处：《现代生物医学进展》2013年第3期573-577,共5页Progress in Modern Biomedicine

基　　金：广东省自然科学基金项目(10151001002000012)

摘　　要：植物芪类化合物,是一类具有抗菌植保作用的次生代谢产物,因具有抑菌、抗氧化、抗肿瘤等多种生物活性而越来越受到重视。本文对植物芪类生物合成途径中涉及到的相关酶、基因和代谢调控机制的研究现状和应用系统生物学研究芪类生物合成途径的相关酶、基因的方法进行综述,并讨论了芪类生物合成相关酶、基因研究的重要意义和应用,以期为调节芪类产量、满足药用保健需求及植物防御、作物品质改良提供帮助。Stilbenes, a kind of secondary metabolites,which function as antimicrobial phytoalexins in plant,have been paid increasingly extensively attention for its activitivies of antibaceteria ,antioxidative and antineoplastic and so on. In this review , the progresses of study on relevant enzymes, genes and metabolic regulation in biosynthesis pathway of stilbenes are described, in order to provide references for its advanced research. Here we introduce a holistic and systematic method of researching in relevant enzymes, genes in biosynthesis pathway of Stilbenes-Systems biology. The application of knowledge of relative enzymes, genes in stilbenes＇ biosynthesis in metabolic engineering which is used as a tool of improving the disease resistance of plants and health caring＇quality of crops is also discussed.

关 键 词：芪类次生代谢物 合成相关酶 代谢调控 系统生物学 生物合成途径 

分 类 号：Q949.95[生物学—植物学] Q282.71