补肾益智汤联合神经节苷酯治疗血管性痴呆  

Therapeutic Effects of Bushen Yizhi Decoction Combined with GM1 on Vascular Dementia

作　　者：李敬会[1] 夏忠诚[1] 桂程丽[1] 

机构地区：[1]湖北医药学院附属人民医院老年病科十堰市老年病研究所,湖北十堰442000

出　　处：《辽宁中医杂志》2013年第3期481-483,共3页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的:探讨补肾益智汤联合神经节苷酯治疗血管性痴呆的疗效。方法:符合血管性痴呆诊断标准的住院患者46例,按入院时间随机分为治疗组和对照组,每组23例。对照组给予神经节苷脂钠静脉滴注,治疗期为21 d。观察组在对照组基础上加用补肾益智汤。采用简易智力状态量表(MMSE)、日常生活评定量表(ADL)在治疗前和治疗21 d后进行评分及血液流变学检验。结果:治疗后与治疗前相比较:治疗组MMSE评分增分明显,差异有统计学意义(P<0.05);ADL评分下降,差异有统计学意义(P<0.05);且治疗后两组MMSE评分、ADL评分比较,差异有统计学意义(P<0.05)。结论:补肾益智汤联合神经节苷酯治疗血管性痴呆有良好疗效,能促进认知功能恢复,提高患者生活质量。Objective ：To investigate the clinical therapeutic effects of Bushen Yizhi Decoction combined with GM1 on vascular dementia. Methods ：46 patients suffering from vascular dementia were randomly divided into two groups （n = 23 ） . The control group was treated with GM1 and the treatment group added Bushen Yizhi decoction based on GM! ,continued for 21 days. Before and after treatment, MMSE, ADL and hemorrheology were respectively used to evaluate the effect. Results ： After treatment, MMSE increased and ADL deduction of treatment group had statistical significance （ P 〈 0.05 ）. And there were significant differences af- ter treatment between two groups （P 〈 0. 05 ）. Conclusion：Bushen Yizhi Decoction combined with GM1 has a higher efficacy on vascular dementia.

关 键 词：补肾益智汤 神经节苷酯 血管性痴呆 

分 类 号：R743[医药卫生—神经病学与精神病学]